中国司法鉴定Issue(6)：58-62,5.DOI:10.3969/j.issn.1671-2072.2024.06.007
P300在外伤性蛛网膜下腔出血所致精神障碍者伤残程度中的评估作用
P300 in Psychiatric Impairment Assessment during Psychiatric Disorders Caused by Traumatic Subarachnoid Hemorrhage
摘要
Abstract
Objective To explore the role of P300 in impairment appraisal during psychiatric disorders caused by traumatic subarachnoid hemorrhage(TSAH).Methods Sixteen patients who met the criteria for organic mental disorders(only caused by TSAH)according to the 10th version of the International Classification of Diseases(ICD-10)were included,along with seventeen healthy controls matched for gender,age,and educational level.P300 detection was conducted on the participants using a visual Oddball paradigm;meanwhile,assessments were made using scales such as the activity of daily living(ADL)scale and the social disability screening schedule(SDSS).Results The P300 amplitudes at points Fz,Cz,CPz,and Pz in the TSAH group were significantly lower than those in the healthy control group(P<0.05).The P300 latencies at points Cz,CPz,and Pz in the TSAH group were prolonged compared to the healthy control group(P<0.05).There was a negative correlation between the amplitudes at points Fz,Cz,CPz,and Pz with the ADL scale and SDSS scores in the TSAH group(P<0.05).Additionally,there was a positive correlation between the P300 latencies at points Cz,CPz,and Pz with ADL scale scores and the P300 latency at point Pz with the SDSS scores in the TSAH group(P<0.05).Conclusion The amplitude of P300 can reflect the severity of mental disorders caused by TSAH,with lower P300 amplitudes indicating more severe conditions.P300 amplitude can serve as a reference indicator for psychiatric impairment appraisal during psychiatric disorders caused by TSAH.关键词
法医精神病学/外伤性蛛网膜下腔出血/精神伤残/事件相关电位/P300Key words
forensic psychiatry/traumatic subarachnoid hemorrhage(TSAH)/psychiatry impairment/event-related potential(ERP)/P300分类
社会科学引用本文复制引用
张盛宇,王书剑,李豪喆..P300在外伤性蛛网膜下腔出血所致精神障碍者伤残程度中的评估作用[J].中国司法鉴定,2024,(6):58-62,5.基金项目
"十四五"国家重点研发计划课题(2022YFC3302001) （2022YFC3302001）
国家自然科学基金项目(81801881) （81801881）
上海市"科技创新行动计划"社会发展科技攻关资助项目(20DZ1200300) （20DZ1200300）
中央级公益性科研院所资助项目(GY2022Z-2,GY2023Z-4) （GY2022Z-2,GY2023Z-4）
上海市法医学重点实验室资助项目(21DZ2270800) （21DZ2270800）
上海市司法鉴定专业技术服务平台资助项目. （）
