阿尔茨海默病及相关病2025，Vol.8Issue(1)：17-21,5.DOI:10.3969/j.issn.2096-5516.2025.01.003
老年慢性心力衰竭合并认知功能障碍患者心衰指标、中医证候与认知功能的相关性研究
Correlation between heart failure indicators,Chinese medicine symptoms,and cognitive function in elderly patients with chronic heart failure combined with cognitive dysfunction
摘要
Abstract
Objective:To investigate the correlation between heart failure indexes,Chinese medicine evidence points,and cognitive function in elderly patients with chronic heart failure(CHF)combined with cognitive impairment(CI).Methods:165 elderly CHF patients were selected,and 92 CHF patients with combined CI were included according to the diagnostic criteria.The Simple Mental State Examination(MMSE)and Montreal Cognitive Assessment Scale(MoCA)were used to assess the severity of cognitive dysfunction in the patients,to complete the Chinese medicine evidence classification and Chinese medicine symptom scores,and to determine the NYHA cardiac function classification,LVEF,BNP,and IMT.The cardiac function classification,LVEF,BNP,duration of the disease,IMT,distribution of the basic Chinese medicine evidence types,and symptom.The correlation between cardiac function classification,LVEF,BNP,disease duration,IMT,Distribution of Basic Chinese Medicine Patterns and Symptom Scores,and cognitive function was analyzed.Results:The MMSE and MoCA scores of elderly patients with CHF combined with CI were not statistically significant(P<0.05);LVEF was positively correlated with MMSE and MoCA scores;NYHA cardiac function classification,BNP,duration of heart failure,and Chinese medicine symptom scores were negatively correlated with MMSE and MoCA scores;and there was no correlation between IMT and MMSE and MoCA scores.Conclusion:In elderly patients with CHF combined with CI,there is a close relationship between NYHA cardiac function classification,BNP,duration of heart failure,LVEF,TCM symptom score,and cognitive function,and elderly patients with CHF should undergo early cognitive function assessment and early intervention.关键词
慢性心力衰竭/认知功能/心功能/中医证候Key words
Chronic heart failure(CHF)/Cognitive function/Cardiac function/Chinese medicine symptoms分类
医药卫生引用本文复制引用
朱小涵,邱文超,岑怡,肖姝雲..老年慢性心力衰竭合并认知功能障碍患者心衰指标、中医证候与认知功能的相关性研究[J].阿尔茨海默病及相关病,2025,8(1):17-21,5.基金项目
国家自然科学基金项目(编号:82374550) （编号:82374550）
上海市浦东新区中医薄弱学科建设项目(编号:PDZY-2020-0406) （编号:PDZY-2020-0406）
国家中医药管理局第五批全国中医临床优秀人才研修项目(国中医药人教函[2022]1号). （国中医药人教函[2022]1号）
