机器人外科学杂志(中英文)2025,Vol.6Issue(1):33-37,5.DOI:10.12180/j.issn.2096-7721.2025.01.007
硬膜外麻醉联合全身麻醉在机器人辅助根治性前列腺切除术患者中的应用效果
Application effect of combined epidural-general anesthesia on patients undergoing robot-assisted radical prostatectomy
摘要
Abstract
Objective:To compare the influences of general anesthesia and combined epidural-general anesthesia on anesthesia effect and perioperative management in robot-assisted prostatectomy.Methods:110 patients who underwent robot-assisted radical prostatectomy from September 2019 to September 2023 in the second affiliated hospital of PLA Air Force Military Medical University were selected and divided into the control group(general anesthesia,n=55)and the study group(epidural anesthesia combined with general anesthesia,n=55)using a hidden random number table.The motor and sensory block,anesthesia effect,inflammatory factors,and complications were compared between the two groups.Results:Comparative analysis revealed that the study group showed a significant shortening trend in the onset time of sensory and the time to reach maximum motor block(P<0.05).Meanwhile,lengths of sensory and motor block were significantly prolonged in the study group(P<0.05).Compared with the control group,the study group had a higher excellent rate(P<0.05)and a lower goodness rate of anesthesia effect(P<0.05).The tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)were all increased in the two groups on the 3rd day after surgery compared with those before surgery(P<0.05),but they were relatively lower in the study group than the control group(P<0.05).The study group experienced a lower incidence rate of complications than the control group(P<0.05).Conclusion:In robot-assisted radical prostatectomy,the epidural anesthesia combined with general anesthesia could provide a faster onset and longer duration of motor and sensory block,better anesthesia effects,more effective inhibition of inflammatory factor release,and fewer complications than general anesthesia alone.关键词
硬膜外联合全身麻醉/机器人辅助手术/根治性前列腺切除术/围手术期管理/炎症因子Key words
Combined Epidural-General Anesthesia/Robot-assisted Surgery/Radical Prostatectomy/Perioperative Management/Inflammatory Factors分类
医药卫生引用本文复制引用
王瑗,陈新超,冯建梅,和优娟..硬膜外麻醉联合全身麻醉在机器人辅助根治性前列腺切除术患者中的应用效果[J].机器人外科学杂志(中英文),2025,6(1):33-37,5.基金项目
陕西省重点研发计划项目(2021SF-054) Key R&D Plan Project of Shaanxi Province(2021SF-054) (2021SF-054)