机器人外科学杂志（中英文）2025，Vol.6Issue(1)：38-44,7.DOI:10.12180/j.issn.2096-7721.2025.01.008
超声引导腹横肌平面阻滞麻醉联合静脉滴注纳布啡在机器人辅助根治性前列腺切除术患者中的应用效果
Effect of ultrasound-guided transversus abdominis plane block combined with intravenous nalbuphine in patients undergoing robot-assisted radical prostatectomy
摘要
Abstract
Objective:To investigate the feasibility of ultrasound-guided transversus abdominis plane block(TAPB)combined with intravenous nalbuphine in patients undergoing robot-assisted radical prostatectomy.Methods:60 patients who underwent robot-assisted radical prostatectomy in Baoji People's Hospital from Nov.2023 to May 2024 were selected and divided into the control group(self-controlled intravenous analgesia,n=30)and the observation group(ultrasound-guided TAPB combined with intravenous nalbuphine,n=30)using a random number table.Clinical indicators of patients in the two groups were statistically compared.Results:The perioperative recovery of patients in the observation group was better than those in the control group(P<0.05).At T0(preoperative),T1(intraoperative 1 h)and T2(postoperative 2 h),diastolic blood pressure(DBP)decreased and then increased,systolic blood pressure(SBP)and heart rate(HR)increased and then decreased in both groups.At T1 and T2,DBP was higher,and SBP and HR were lower in the observation group than those in the control group(P<0.05).At T0,T1,and T2,the partial pressure of oxygen(PaO2)and oxygenation index(OI)decreased and then increased,and the partial pressure of carbon dioxide(PaCO2)increased and then decreased in the two groups.At T1 and T2,PaO2 and OI were higher,and PaCO2 was lower in the observation group than those in the control group(P<0.05).At T2,T3(postoperative 6 h),T4(postoperative 12 h),and T5(postoperative 24 h),visual analogue scale(VAS)scores in both groups decreased gradually,and the scores in the observation group were relatively lower(P<0.05).At T0,T1,and T2,the serum levels of epinephrine,norepinephrine and cortisol were increased and then decreased in the two groups,and the serum levels of E,NE and Cor at T1 and T2 were relatively lower in the observation group(P<0.05).The incidence of postoperative complications was lower in the observation group than the control group(P<0.05).Conclusion:In patients undergoing robot-assisted radical prostatectomy,the clinical application of ultrasound-guided TAPB combined with nalbuphine intravenous is effective.It can accelerate the postoperative rehabilitation,provide a high postoperative analgesia,stabilize hemodynamics and respiratory function,as well as reduce the stress response caused by surgery and anesthesia,and lower the risk of complications.关键词
超声引导/腹横肌平面阻滞/纳布啡/机器人辅助手术/根治性前列腺切除术Key words
Ultrasound-guided/Transverse Abdominal Plane Block/Nalbuphine/Robot-assisted Surgery/Radical Prostatectomy分类
医药卫生引用本文复制引用
马亚芳,陈治富,闫岸军..超声引导腹横肌平面阻滞麻醉联合静脉滴注纳布啡在机器人辅助根治性前列腺切除术患者中的应用效果[J].机器人外科学杂志（中英文）,2025,6(1):38-44,7.基金项目
陕西省重点研发计划项目(2021SF-265) Key R&D Plan Project of Shaanxi Province(2021SF-265) （2021SF-265）
