环境与职业医学2024，Vol.41Issue(12)：1341-1348,8.DOI:10.11836/JEOM24248
氯化多氟烷基醚磺酸母婴暴露水平及对其健康的影响
Levels and health effects of maternal and infant exposure to chlorinated polyfluorinated ether sulfonic acid
摘要
Abstract
Chlorinated polyfluoroalkyl ether sulfonic acid(Cl-PFESA,trade name F-53B),a substitute for perfluorooctane sulfonate(PFOS),notably featuring 6:2 Cl-PFESA and 8:2 Cl-PFESA as its pri-mary components,are the most biologically persistent per-and polyfluoroalkyl substances(PFAS)currently known.Since its initial synthesis in China in 1975,F-53B has served as an antifogging agent in the electroplating industry for over four decades.Recently,F-53B has been detected across various matrix and human samples,ranking among the top three PFAS concentrations in maternal and umbilical cord blood sera in China,according to available epidemiological studies.Current limited epidemiological studies indicate that F-53B poses multiple adverse effects on maternal and infant health.Therefore,this article reviewed the exposure levels of F-53B in mothers and infants,along with its adverse health effects,thereby providing insights for evaluating the toxic effects of F-53B on maternal and infant health and establishing safety thresholds.关键词
全氟及多氟烷基物质/氯化多氟烷基醚磺酸/6:2氯代全氟醚磺酸盐/8:2氯代全氟醚磺酸盐/母婴健康Key words
per-and polyfluoroalkyl substances/chlorinated polyfluorinated ether sulfonic acid/6:2 chlorinated polyfluorinated ether sulfonic acid/8:2 chlorinated polyfluorinated ether sulfonic acid/maternal and infant health分类
医药卫生引用本文复制引用
曹玉洁,田英,高宇..氯化多氟烷基醚磺酸母婴暴露水平及对其健康的影响[J].环境与职业医学,2024,41(12):1341-1348,8.基金项目
上海市卫生健康委2020年协同创新集群项目(2020CXJQ01) （2020CXJQ01）
上海市加强公共卫生体系建设三年行动计划项目(2023-2025年)(GWVI-4、GWVI-11.1-41) （2023-2025年）
上海市科委自然科学基金项目(22ZR1435600) （22ZR1435600）
