环境与职业医学2024，Vol.41Issue(12)：1432-1437,6.DOI:10.11836/JEOM24142
BaP暴露对女性生殖系统的影响及致病机理的研究进展
Progress on effects of BaP exposure on female reproductive system and pathogenic mechanisms
摘要
Abstract
Benzo[a]pyrene(BaP)is the most abundant environmental pollutant among polycyclic aromatic hydrocarbons(PAHs),and is widely distributed in air,water,soil,barbecue,and fried foods.Human beings are inevitably exposed to BaP.Studies have shown that BaP is reproductively toxic and is involved in diseases related to the female reproductive system by affecting the secretion of ovarian hormones,interfering with the function of ovarian mitochondria(affecting oocyte matu-ration),affecting embryo development(interfering with the migration of trophoblast cells,inva-sion,proliferation,apoptosis)and the process of metaplasia.This article summarized the research progress on the associations between BaP exposure and female reproductive function,miscar-riage,and reproductive system tumors based on relevant studies at home and abroad in recent years,with a view to providing a basis and new direction for future research.关键词
苯并[a]芘/女性生殖/滋养细胞/蜕膜化/流产Key words
Benzo[a]pyrene/female reproduction/trophoblast/decidualization/miscarriage分类
医药卫生引用本文复制引用
高倩倩,冯晓玲..BaP暴露对女性生殖系统的影响及致病机理的研究进展[J].环境与职业医学,2024,41(12):1432-1437,6.基金项目
国家自然科学基金项目(82174421) （82174421）
黑龙江省自然科学基金项目(ZD2021H006) （ZD2021H006）
