应用化学2025，Vol.42Issue(1)：1-13,13.DOI:10.19894/j.issn.1000-0518.240199
表面增强拉曼光谱的基底设计及其血液检测研究进展
Substrate Design of Surface-Enhanced Raman Spectroscopy and Research Progress in the Detection of Body Fluids
摘要
Abstract
Surface enhanced Raman spectroscopy(SERS)has been extensively studied in the field of medical testing due to its unique advantages of rapid detection,high sensitivity,low detection limits and non-destructive analysis.The successful construction of SERS substrates is essential for realizing these benefits.In this paper,the enhancement mechanism of SERS is introduced,the design of its enhanced substrate in blood detection is categorized and discussed.It is divided into two categories:label-free substrates and label substrates,and further subdivided according to different material applications and substrate design methods.A review of relevant literature on the application of SERS detection in blood testing in recent years,summarizes the design methods and application characteristics of different types of enhanced substrates in blood testing.Finally,the design of SERS-enhanced substrate in blood examination is summarized and prospected.关键词
表面增强拉曼光谱/增强机制/无标签基底/有标签基底/血液检测Key words
Surface-enhanced Raman spectroscopy/Enhancement mechanism/Label-free substrate/Label substrate/Blood testing分类
化学化工引用本文复制引用
蔡云帆,许克惠,赵耀,李之婷,夏凌云,王晨语,罗志晓,牛丽娜..表面增强拉曼光谱的基底设计及其血液检测研究进展[J].应用化学,2025,42(1):1-13,13.基金项目
陕西省重点科技创新团队项目(No.2020TD-033)和国家口腔疾病临床医学研究中心一般基金项目(No.LCB202209)资助 Supported by the Shaanxi Key Scientific and Technological Innovation Team(No.2020TD-033)and the National Clinical Research Center for Oral Diseases(No.LCB202209) （No.2020TD-033）
