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Analyzing the Cytotoxic and Genetic Impact of Datura stramonium Extract on MCF7 and HT29 Cancer Cells:A Metabolite and Gene Expression Study

Fayez Althobaiti Hadeer Darwish Raghad Alruqayb Saqer S.Alotaibi Fahad E.Alharthi Ibrahim Jafri Sarah Awwadh Altalhi Ghadi Alsharif Hussam Awwadh E Althagafi Hesham Noureldeen Sarah Alharthi Jawaher Albaqami Najla Amin T.Al Kashgry Ahmed Noureldeen

Phyton-International Journal of Experimental Botany2025，Vol.94Issue(1)：P.181-198,18.

Phyton-International Journal of Experimental Botany2025，Vol.94Issue(1)：P.181-198,18.DOI:10.32604/phyton.2025.059387

Analyzing the Cytotoxic and Genetic Impact of Datura stramonium Extract on MCF7 and HT29 Cancer Cells:A Metabolite and Gene Expression Study

Fayez Althobaiti ¹Hadeer Darwish ¹Raghad Alruqayb ¹Saqer S.Alotaibi ¹Fahad E.Alharthi ²Ibrahim Jafri ¹Sarah Awwadh Altalhi ¹Ghadi Alsharif ³Hussam Awwadh E Althagafi ⁴Hesham Noureldeen ⁵Sarah Alharthi ⁶Jawaher Albaqami ²Najla Amin T.Al Kashgry ²Ahmed Noureldeen²

作者信息

1. Department of Biotechnology,College of Science,Taif University,Taif,21944,Saudi Arabia
2. Department of Biology,College of Science,Taif University,Taif,21944,Saudi Arabia
3. Department of Clinical Laboratory Sciences,College of Applied Medical Sciences,King Saud Bin Abdulaziz University for Health Sciences,Jeddah,21423,Saudi Arabia Department of Biomedical Research,King Abdullah International Medical Research Center,Jeddah,21423,Saudi Arabia
4. Biology Department,Faculty of Science and Arts,Al-Baha University,Al-Mikhwah,65731,Saudi Arebia
5. Faculty of Medicine,Mansoura University,Mansoura,35516,Egypt
6. Department of Chemistry,Collage of Science,Taif University,Taif,21944,Saudi Arabia
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摘要

关键词

Datura stramonium/secondary metabolites/GC-MS analysis/cytotoxicity/breast and colon cancer cell lines/MTT assay

分类

农业科技

引用本文复制引用

Fayez Althobaiti,Hadeer Darwish,Raghad Alruqayb,Saqer S.Alotaibi,Fahad E.Alharthi,Ibrahim Jafri,Sarah Awwadh Altalhi,Ghadi Alsharif,Hussam Awwadh E Althagafi,Hesham Noureldeen,Sarah Alharthi,Jawaher Albaqami,Najla Amin T.Al Kashgry,Ahmed Noureldeen..Analyzing the Cytotoxic and Genetic Impact of Datura stramonium Extract on MCF7 and HT29 Cancer Cells:A Metabolite and Gene Expression Study[J].Phyton-International Journal of Experimental Botany,2025,94(1):P.181-198,18.

基金项目

Taif University,Saudi Arabia,Project No.(TU-DSPP-2024-74). （TU-DSPP-2024-74）

Phyton-International Journal of Experimental Botany

ISSN：0031-9457

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