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中医药精准诊疗新范式的发展构想OA北大核心

Development of a new paradigm for precision diagnosis and treatment in traditional Chinese medicine

中文摘要英文摘要

中医药诊疗发展经历了从零星经验、辨证论治再到病证结合的多种范式阶段,目前是我国中西医并重医学体系的重要组成部分.辨证论治既体现了个性化治疗又体现了整体性思维,但是辨证的一致性问题影响了临床疗效.当前的病证结合存在中医药和西医药简单合用问题,中西医协同优势体现不充分.近年来,在诊疗理念发展和分析技术进步的推动下,西医学正从传统生物模式快速向精准医学模式转变,中医药学也面临从传统辨证论治和病证结合模式向精准诊疗范式发展的问题.与西医微观精准趋向不同,中医药精准诊疗主要体现在数据驱动的全信息应用,包括辨证精准化、用药精准化、疾病管理精准化和疗效评价精准化等不同层面.当前发展的重点任务是加快中医药精准诊疗技术平台开发和学科建设.

The development of traditional Chinese medicine(TCM)diagnosis and treatment has undergone multiple paradigms,evolving from sporadic experiential practices to systematic approaches in syndrome differentiation and treatment and further integration of disease and syndrome frameworks.TCM is a vital component of the medical system,valued alongside Western medicine.Treatment based on syndrome differentiation embodies both personalized treatment and holistic approaches;however,the inconsistency and lack of stability in syndrome differentiation limit clinical efficacy.The existing integration of diseases and syndromes primarily relies on patchwork and embedded systems,where the full advantages of synergy between Chinese and Western medicine are not fully realized.Recently,driven by the development of diagnosis and treatment concepts and advances in analytical technology,Western medicine has been rapidly transforming from a traditional biological model to a precision medicine model.TCM faces a similar need to progress beyond traditional syndrome differentiation and disease-syndrome integration toward a more precise diagnosis and treatment paradigm.Unlike the micro-level precision trend of Western medicine,precision diagnosis and treatment in TCM is primarily reflected in data-driven applications that incorporate information at various levels,including precise syndrome differentiation,medication,disease management,and efficacy evaluation.The current priority is to accelerate the development of TCM precision diagnosis and treatment technology platforms and advance discipline construction in this area.

倪敬年;魏明清;李婷;时晶;肖伟;程京;丛斌;张伯礼;田金洲

北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700南京中医药大学清华大学河北医科大学天津中医药大学北京中医药大学东直门医院 北京 100700

中医学

中医药辨证论治病证结合精准诊疗范式

traditional Chinese medicinesyndrome differentiation and treatmentcombination of diseases and syndromesprecision diagnosis and treatmentparadigm

《北京中医药大学学报》 2025 (1)

43-47,5

中国工程院战略研究与咨询项目(No.2023-PP-05,No.2022-XY-33,No.2022-XBZD-15-04)北京中医药大学解码中医项目(No.BZY-JMZY-2022-002) Strategic Research and Consulting Project of the Chinese Academy of Engineering(Nos.2023-PP-05,2022-XY-33,and 2022-XBZD-15-04)

10.3969/j.issn.1006-2157.2025.01.006

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