Osteopontin deficiency promotes cartilaginous endplate degeneration by enhancing the NF-κB signaling to recruit macrophages and activate the NLRP3 inflammasome
Yanqiu Wang Changqing Li Hongli Li Yue Zhou Minghan Liu Wanqian Zhang Yi Yang Jinghao Qin Ruoyu Wang Shuai Wang Wenjuan Fu Qin Niu Yanxia Wang
骨研究(英文版)2024,Vol.12Issue(4):846-862,17.
骨研究(英文版)2024,Vol.12Issue(4):846-862,17.DOI:10.1038/s41413-024-00355-3
Osteopontin deficiency promotes cartilaginous endplate degeneration by enhancing the NF-κB signaling to recruit macrophages and activate the NLRP3 inflammasome
Osteopontin deficiency promotes cartilaginous endplate degeneration by enhancing the NF-κB signaling to recruit macrophages and activate the NLRP3 inflammasome
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Yanqiu Wang,Changqing Li,Hongli Li,Yue Zhou,Minghan Liu,Wanqian Zhang,Yi Yang,Jinghao Qin,Ruoyu Wang,Shuai Wang,Wenjuan Fu,Qin Niu,Yanxia Wang..Osteopontin deficiency promotes cartilaginous endplate degeneration by enhancing the NF-κB signaling to recruit macrophages and activate the NLRP3 inflammasome[J].骨研究(英文版),2024,12(4):846-862,17.基金项目
This research was supported by Chongqing Municipal Natural Science Foundation(CSTB2022NSCQ-MSX1366),National Natural Science Foundation of China(81702182,81874087),Chongqing Outstanding Young Talent Supporting Program(cstc2024ycjh-bgzxm0031),and the Special Project for Talent Development of Xinqiao Hospital(2022XKRC006).We would like to thank the Experimental Center of Basic Medicine of Army Medical University for their generous assistance. (CSTB2022NSCQ-MSX1366)