摘要
Abstract
[Objective]A new method for simultaneous determination of 15 perfluorinated compounds in water is established by online solid-phase extraction-ultra-high performance liquid chromatography-tandem quadrupole mass spectrometry(online SPE-LC/MS/MS).[Methods]After simple pretreatment,the water samples were subjected to online SPE and enriched on a WAX column,followed by direct elution onto a C18 analytical column for gradient elution.Detection was performed under the dynamic multiple reaction monitoring mode of the mass spectrometer,and quantification was achieved using the internal standard method.This enabled rapid detection of 15 perfluorinated compounds in water.The linearity range,detection limits,limits of quantitation,and precision of this method were investigated.[Results]The results indicated that the 15 target perfluorinated compounds exhibited good linearity within the mass concentration range of 4 ng/L to 400 ng/L,with correlation coefficients(r)exceeding 0.999.The limits of detection ranged from 0.6 ng/L to 2.4 ng/L,while the limits of quantification ranged from 2.4 ng/L to 9.6 ng/L.Meanwhile,six different types of syringe filters(regenerated cellulose membrane,nylon membrane,glass fiber membrane,mixed cellulose ester membrane,polyethersulfone membrane,and acetate fiber membrane)were selected for comparison of recovery rates.The results showed that the glass fiber membrane was the most effective,more suitable for water sample filtration in this method.Representative effluent and corresponding source water were selected for determination of spiked recovery rates at high,medium and low concentrations,with spiked recovery rates of the two types of water samples ranging from 71.8％to 122.2％.[Conclusion]Compared with conventional offline solid-phase extraction methods,this method has advantages such as requiring less water sample volume and simpler pretreatment processes,providing a new approach for detecting perfluorinated compounds in water.关键词
在线固相萃取/超高效液相色谱-串联质谱/水中全氟化合物/针式过滤器/滤膜材质Key words
online solid phase extraction/ultra-performance liquid chromatography-tandem mass spectrometry/perfluorinated compounds in water/needle filter/membrane material分类
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