昆明医科大学学报2025，Vol.46Issue(2)：80-87,8.DOI:10.12259/j.issn.2095-610X.S20250212
高血压患者体力活动时长、睡眠质量及体重控制对患者报告结局的影响
The Effects of Physical Activity Duration,Sleep Quality,and Weight Control on Patient-Reported Outcomes in Hypertensive Patients
摘要
Abstract
Objective To investigate the correlation between physical activity duration,sleep quality,weight control,and PRO(patient-reported outcomes)in individuals with hypertension,providing effective information for enhancing patient-reported outcomes in this population.Methods A total of 625 hypertensive patients were randomly selected from four counties in Yunnan Province from April to June 2020 to participate in a field survey.The questionnaire included patients'basic information,lifestyle,health status and the PRO Scale for Hypertension-PROISCD-HY(V1.0).Statistical analyses including t-tests,one-way ANOVA,and multivariate linear regression were conducted to investigate the relationships between physical activity duration,sleep quality,weight control,and PRO,with the Bootstrap method used to examine potential mediating effects.Results After adjusting for potential covariates,the multiple linear regression model indicated a significant association between a physical activity duration of≥2 hours with PRO[B=6.551,95%CI(2.611,10.491)].Stratified analysis showed that this association was only present among males,females,and younger adults,but not in older adults.Additionally,a positive correlation was found between good sleep quality and PRO[B=1.870,95%CI(0.449,3.291)],with this association being consistent across all populations after stratification.Patients who managed their condition through exercise and diet had higher PRO scores[B=1.904,95%CI(0.383,3.424)],while those controlling weight through diet and other methods exhibited a decrease in PRO scores[B=-4.873,95%CI(-7.860,-1.887);B=-7.105,95%CI(-12.211,-1.999)],with variations among different groups.The bootstrap method revealed that physical activity duration had both direct and indirect effects on PRO,with sleep quality acting as a partial mediator between physical activity duration and PRO.Conclusion A Physical activity duration of at least 2 hours,good sleep quality,and weight control have been shown to improve PRO in individuals with hypertension.关键词
高血压/患者报告结局/多元线性回归/BootstrapKey words
Hypertension/Patient-reported outcomes/Multiple linear regression/Bootstrap分类
医药卫生引用本文复制引用
张茹,赵雅静,张雯,唐顺定,王涵,张晓磬..高血压患者体力活动时长、睡眠质量及体重控制对患者报告结局的影响[J].昆明医科大学学报,2025,46(2):80-87,8.基金项目
云南省科技厅-昆明医科大学应用基础研究联合专项面上项目(202401AY070001-067) （202401AY070001-067）
云南省科技厅基础研究计划(202101AY070001-221) （202101AY070001-221）
云南省科技厅基础研究计划(202101AY070001-222) （202101AY070001-222）
昆明医科大学硕士研究生创新基金(2024S169) （2024S169）
