临床小儿外科杂志2024，Vol.23Issue(12)：1144-1148,5.DOI:10.3760/cma.j.cn101785-202308020-007
新生儿肠闭锁合并胎粪性腹膜炎患儿并发短肠综合征的临床特征分析
Analysis of clinical features of neonatal intestinal atresia complicated with meconium peritonitis in chil-dren of short bowel syndrome
摘要
Abstract
Objective To explore the clinical characteristics of intestinal atresia(IA)complicated by meconium peritonitis(MP)in neonatorum with short bowel syndrome(SBS).Methods From January 2019 to May 2023,the relevant clinical data were retrospectively reviewed for 33 IA children with MP.A total of 14 patients failing to disintegrate from intravenous nutrition at Day 4 post-operation were included in short bowel syndrome(SBS)group.There were 7 boys and 7 girls with an age range of(2-30)day.Another 19 children with a complete bowel recovery within 42d were included in non-short bowel syndrome(Non-SBS)group.There were 12 boys and 7 girls with an age range of(4-33)day.Prenatal ultrasonography,gender,gestational age,birth weight,clinical manifestations,surgical findings,initial feeding time,initial defecation time(through fistula or anus),parenteral nutrition time,hospitalization stay and survival rate were compared between two groups.Results The incidence of SBS was 42.4％(14/33).No significant inter-group differences existed in gender,gestational age,birth weight or age at admission(P＞0.05).Abnormal rate of prenatal ultrasonography in SBS and non-SBS groups were 85.7％(12/14)and 42.1％(8/19),respectively.Proportion of children undergoing high enterostomy was 78.6％(11/14)and 31.6％(4/19),duration of parenteral nutrition 79(64,120)and 17(12,21)day and duration of hospitalization 87(48,125)and 24(17,30)day with statistical significance(P＜0.05).No significant inter-group differences existed in abdominal distension,vomiting,preoperative intes-tinal dilation or initial defecation time(P＞0.05).Survival rate of SBS and non-SBS groups was 85.7％(12/14)and 94.7％(18/19)with no statistical significance(P＞0.05).Conclusions Abnormal fetal ultra-sonography of neonatal intestinal atresia complicated with MP hints at a higher postoperative probability of SBS.This type of SBS may be cured conventionally.关键词
胎粪性腹膜炎/肠闭锁/短肠综合征/外科手术/儿童Key words
Meconium Peritonitis/Intestinal Atresia/Short Bowel Syndrome/Surgical Procedures,Op-erative/Child引用本文复制引用
邹婵娟,李波,董洁,李明,冯勇,夏仁鹏,周崇高..新生儿肠闭锁合并胎粪性腹膜炎患儿并发短肠综合征的临床特征分析[J].临床小儿外科杂志,2024,23(12):1144-1148,5.基金项目
湖南省出生缺陷协同防治科技重大专项(2019SK1015) Major Birth Defect Collaborative Prevention and Control Technology Project of Hunan Province(2019SK1015) （2019SK1015）
