上海针灸杂志2025，Vol.44Issue(2)：164-169,6.DOI:10.13460/j.issn.1005-0957.2025.02.0164
针刺联合中药治疗非小细胞肺癌术后顽固性咳嗽的疗效观察
Therapeutic observation of acupuncture plus Chinese medication in treating chronic cough after surgery for non-small-cell lung cancer
摘要
Abstract
Objective To observe the clinical efficacy of acupuncture plus Jin Shui Liu Jun Jian in treating chronic cough after surgery for non-small-cell lung cancer(NSCLC).Method Eighty-two participants with chronic cough after NSCLC surgery were allocated to a treatment group and a control group using the random number table method,with 41 cases in each group.Both groups received basic intervention to relieve cough and reduce sputum.In addition,the control group was prescribed oral administration of Jin Shui Liu Jun Jian,and the treatment group received the same medication combined with acupuncture therapy.The clinical efficacy and adverse reaction rate were compared between the two groups.Before and after the treatment,the two groups were observed for changes in the traditional Chinese medicine(TCM)pattern score,pulmonary function,and serum inflammatory factor levels.Result The total effective rate was higher in the treatment group than in the control group(P＜0.05).After the treatment,the scores of cough and panting,shortness of breath and chest tightness,and thin white sputum were lower in the treatment group compared to the control group(P＜0.05),and the forced expiratory volume in the first second(FEV1),forced vital capacity(FVC),FEV1/FVC,and peak expiratory flow(PEF)were higher in the treatment group(P＜0.05).After the treatment,the serum levels of interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),eosinophil(EOS),and interleukin-10(IL-10)were lower in the treatment group compared to the control group(P＜0.05).There was no significant difference in the adverse rate between the two groups(P＞0.05).Conclusion Based on the treatment for relieving cough and reducing sputum,acupuncture plus Jin Shui Liu Jun Jian can produce more significant clinical efficacy than using the Chinese medication alone in treating chronic cough after NSCLC surgery;this combined method can more effectively reduce cough and sputum,improve pulmonary function,and alleviate inflammatory reactions.关键词
针刺疗法/针药并用/慢性咳嗽/癌,非小细胞肺/术后/肺功能Key words
Acupuncture therapy/Acupuncture medication combined/Chronic cough/Carcinoma,Non-small-cell lung/Postoperative/Pulmonary function分类
医药卫生引用本文复制引用
王皓,张海涛,李静,朱紧超,吴雅楠,张勇,吕梅..针刺联合中药治疗非小细胞肺癌术后顽固性咳嗽的疗效观察[J].上海针灸杂志,2025,44(2):164-169,6.基金项目
河北省中医药管理局科研计划项目(2022431) （2022431）
