上海针灸杂志2025，Vol.44Issue(2)：177-182,6.DOI:10.13460/j.issn.1005-0957.2025.02.0177
针灸督脉联合中药治疗缺血性卒中的疗效观察及对脑动脉血流动力学的影响
Observation on the efficacy of Du meridian acupuncture and combined with Chinese medicines in the treatment of ischemic stroke and its effect on cerebral arterial hemodynamics
摘要
Abstract
Objective To observe the clinical efficacy and effects of the combination of Du meridian acupuncture and modified Bu Yang Huan Wu decoction in the treatment of ischemic stroke and its effect on cerebral arterial hemodynamics,neurological function and serum related factor levels of the patients.Method A total of 110 patients with ischemic stroke of blood stasis due to qi deficiency pattern were selected and randomly divided into a control group and an observation group,with 55 cases in each group.Both groups received basic treatment,the control group was treated with modified Bu Yang Huan Wu decoction orally,and the observation group was treated with Du meridian acupuncture on the basis of oral modified Bu Yang Huan Wu decoction in the control group.The clinical efficacy and the occurrence of adverse reactions were compared between the two groups,and the changes of traditional Chinese medicine(TCM)pattern score,cerebral artery hemodynamic indexes,neurological function indexes and serum related factor levels before and after treatment were observed in the two groups.Result The total effective rate of the observation group was higher than that of the control group(P＜0.05).TCM pattern score,National Institutes of Health stroke scale(NIHSS)score,cerebral arterial hemodynamic indexes[peak systolic velocity(PSV),mean velocity(Vm),and end-diastolic volume(EDV)]and serum-related factors[caveolin-1(Cav-1),pentraxin 3(PTX3)and visinin-like protein-1(VILIP-1)]were better than those in the same group before treatment(P＜0.05),and the above indexes in the observation group were better than those in the control group after treatment(P＜0.05).No significant adverse reactions occurred in both groups.Conclusion On the basis of basic treatment,the combination of Du meridian acupuncture and modified Bu Yang Huan Wu decoction in the treatment of ischemic stroke can more effectively improve the level of cerebral arterial hemodynamics and promote the recovery of neurological function,and the clinical efficacy of this treatment is better than that of the oral modified Bu Yang Huan Wu decoction alone,and there are no significant adverse events.关键词
针灸疗法/放血疗法/针药并用/脑梗死/卒中/神经功能/血液流变学Key words
Acupuncture therapy/Bloodletting therapy/Acupuncture medication combined/Cerebral infarction/Stroke/Neurological function/Hemorheology分类
医药卫生引用本文复制引用
孟占鹏,郭子华,张丹,刘作印..针灸督脉联合中药治疗缺血性卒中的疗效观察及对脑动脉血流动力学的影响[J].上海针灸杂志,2025,44(2):177-182,6.基金项目
河南省中医药科学研究专项课题(2023ZY2170) （2023ZY2170）
