基于多模式影像技术观察针刺对卒中后肢体功能障碍的影响OA

Objective To observe the effect of acupuncture on post-stroke limb dysfunction by multimodal imaging technique.Method A total of 116 patients with ischemic stroke confirmed by cranial MRI were selected and randomly divided into an acupuncture group(60 cases)and a rehabilitation group(56 cases).The rehabilitation group was treated with secondary prevention drugs for cerebrovascular diseases and routine neurological treatment,and was accompanied by limb function rehabilitation training;the acupuncture group was treated with acupuncture on the basis of the rehabilitation group.The Brunnstrom stage changes,apparent diffusion coefficient(ADC)and fractional anisotropy(FA)in diffusion tensor image(DTI)and cerebral perfusion imaging to detect infarct area and collateral circulation were compared between the two groups before and after treatment.Result After treatment,Brunnstrom staging was better in the acupuncture group than in the rehabilitation group(P＜0.05).The ADC value of both groups was lower than that before treatment(P＜0.05),and the FA value of both groups was higher than that before treatment(P＜0.05).The infarct area of both groups did not progress significantly compared with that before treatment(P＞0.05),decreased slightly but not significantly.The collateral circulation of both groups improved significantly after treatment(P＜0.05),and the collateral circulation of the acupuncture group was better than that of the rehabilitation group after treatment(P＜0.05).Conclusion On the basis of conventional treatment and rehabilitation training,acupuncture may improve limb function after stroke by stimulating the primary cortex to be active,increasing cerebral blood flow,especially increasing peri-infarct collateral circulation,strengthening the connectivity between the motor cortex in the infarcted area and the related brain areas,and further activating the function of the cortical fiber tracts.