外科理论与实践2024，Vol.29Issue(5)：409-413,5.DOI:10.16139/j.1007-9610.2024.05.08
前哨淋巴结阴性乳腺癌病人非前哨淋巴结转移相关危险因素分析
Analysis of risk factors for non-sentinel lymph node metastasis in patients with sentinel lymph node-negative breast cancer
摘要
Abstract
Objective To analyze the risk factors for non-sentinel lymph node(NSLN)metastasis in patients with sentinel lymph node(SLN)-negative breast cancer.Methods Patients with breast cancer who underwent mastectomy and SLN biopsy at our center between January 2009 and August 2024 were retrospectively included.Univariate and multivariate analyses were performed in SLN-negative populations underwent low axillary lymph node dissection to identify risk factors for NSLN metastasis.Results A total of 2 387 SLN-negative patients were included,including 2 288(95.9%)without NSLN metastasis and 99(4.1%)with NSLN metastasis.Univariate and multivariate analyses showed that lymphovascular invasion(LVI)was an independent risk factor for NSLN metastasis in SLN-negative patients(13.5%versus 3.5%;OR=4.14,95%CI:2.27-7.56,P＜0.001).Patients with multicentric breast cancer showed a trend towards higher risk of NSLN metastasis compared to other types of breast cancer(9.5%versus 4.1%;OR=2.08,95%CI:0.90-4.81,P=0.089).Conclusions Patients with SLN-negative biopsy who have LVI or multicentric breast cancer are at higher risk for NSLN metastasis.关键词
乳腺癌/前哨淋巴结/非前哨淋巴结转移/脉管癌栓/多中心性乳腺癌Key words
Breast cancer/Sentinel lymph node(SLN)/Non-sentinel lymph node(NSLN)metastasis/Lymphovascular invasion(LVI)/Multicentric breast cancer分类
医药卫生引用本文复制引用
张丰哲,童一苇,陈小松,沈坤炜..前哨淋巴结阴性乳腺癌病人非前哨淋巴结转移相关危险因素分析[J].外科理论与实践,2024,29(5):409-413,5.基金项目
Innovative research team of high-level local universities in Shanghai(SHSMU-ZDCX20212200) （SHSMU-ZDCX20212200）
