中国草食动物科学2025，Vol.45Issue(1)：77-83,7.DOI:10.3969/j.issn.2095-3887.2024.00.113
金黄色葡萄球菌噬菌体的特性及其在畜牧业中的应用
Properties of Staphylococcus Aureus Bacteriophages and Their Application in Animal Husbandry
摘要
Abstract
As a natural antibacterial substance,bacteriophage has the advantages of easy access,low mutation rate,small adverse reactions,high specificity,high efficiency,and no harm to commensal bacteria,and can be used as the preferred drug to replace antibiotics.The host range of bacteriophage is a key indicator to evaluate the therapeutic po-tential of bacteriophages,and is of great significance for the selection of bacteriophages,the formulation of treatment strategies and the final efficacy,which is mainly determined by the receptor-binding proteins of the phage and the spe-cific receptors on the surface of the host cells.In this paper,the classification structure of Staphylococcus aureus phages,receptor-binding proteins,the discovery of host surface homologous receptors,and the application of bacterio-phage therapy in animal husbandry were expounded,in order to provide reference for the prevention and control of Staphylococcus aureus disease.关键词
噬菌体/金黄色葡萄球菌/受体结合蛋白Key words
bacteriophage/staphylococcus aureus/receptor-binding proteins分类
农业科技引用本文复制引用
金炳甜,路頔,杜鹏程,杨馨郁,吉尔叁也,杨峰,董鹏程..金黄色葡萄球菌噬菌体的特性及其在畜牧业中的应用[J].中国草食动物科学,2025,45(1):77-83,7.基金项目
国家重点研发计划项目(2022YFD1302101) （2022YFD1302101）
甘肃省自然科学基金重点项目(23JRRA564) （23JRRA564）
