中国肺癌杂志2024，Vol.27Issue(12)：911-918,8.DOI:10.3779/j.issn.1009-3419.2024.101.33
云南省肿瘤医院2013-2022年15,967例肺癌手术患者临床流行病学特征分析
Analysis of Clinical Epidemiological Characteristics of 15,967 Lung Cancer Surgery Patients in Yunnan Cancer Hospital from 2013 to 2022
摘要
Abstract
Background and objective Lung cancer is a disease with a high incidence rate in Yunnan province,yet there is a paucity of large-scale studies on its clinical epidemiology.This research aims to investigate the epidemiological characteristics of patients who underwent lung cancer surgery at Yunnan Cancer Hospital over the past decade,thereby pro-viding a theoretical basis for the prevention and treatment of lung cancer.Methods Clinical data were collected from 15,967 patients who underwent lung cancer surgery at Yunnan Cancer Hospital between 2013 and 2022.A statistical analysis was con-ducted on the patients'general data,surgical information,pathological types of lung cancer,and other clinical epidemiological characteristics.Results Among the 15,967 cases of lung cancer,46.3%were male and 53.7%were female,with the male-to-female ratio ranging from 0.68 to 1.61:1.The median age was 56 years(interquartile range:49-63),and 37.0%of the patients were in the age group of 50-59 years.Since 2017,there has been an annual increase in the proportion of patients under the age of 60 years.The smoking status of the patients showed that 28.1%were smokers and 71.9%were non-smokers.Qujing city accounted for 41.4%and Kunming city for 23.2%of the cases in Yunnan province,with 29.6%of patients originating from Xuanwei and Fuyuan areas of Qujing city.The distribution of affected lung lobes was as follows:right upper lobe 28.2%,right middle lobe 6.3%,right lower lobe 20.1%,leftupper lobe 22.7%,and leftlower lobe 16.4%.The use of thoracoscopic surgery increased from 30.8%to 96.3%,with single-port thoracoscopic surgery comprising 61.3%.Lobectomy was performed in 64.2%of cases,wedge resection in 17.2%,and segmentectomy in 12.2%.The proportion of lobectomy decreased from 83.1%to 46.1%.The proportion of patients in stages 0-I increased from 43.5%to 82.8%,while stages II-IV decreased from 56.5%to 17.2%.Adenocarcinoma increased from 75.6%to 88.3%,and squamous cell carcinoma decreased from 21.5%to 8.6%.Among adenocarcinoma patients,60.9%were female.Among sguamous cell carcinoma patients,90.6%were male.The peak age for adenocarcinoma was 50-59 years,and for squamous cell carcinoma,it was 60-69 years.The smoking rate was higher among squamous cell carcinoma patients(65.9%)compared to adenocarcinoma patients(22.3%).Adenocarcinoma patients had a higher proportion in stages 0-I(76.3%),while squamous cell carcinoma patients were more prevalent in stages II-III(64.1%).Conclusion The findings indicate an increasing proportion of female patients with adenocarcinoma,a younger age of onset,a higher proportion of non-smoking lung cancer patients,and an increased proportion of stages 0-I lung cancer.These trends may reflect the epidemiological characteristics of patients undergoing lung cancer surgery in Yunnan and surrounding areas over the past decade.关键词
肺肿瘤/手术/流行病学/病理类型/云南Key words
Lung neoplasms/Surgery/Epidemiology/Pathological type/Yunnan引用本文复制引用
唐如科,杨凯云,陈小波,杨加鹏,赵敏,向柄全,黄秋博,罗光灿,张宏伟,黄云超,雷玉洁,叶联华,赵光强,向旭东,李高峰,李光剑,王曦,陈颖..云南省肿瘤医院2013-2022年15,967例肺癌手术患者临床流行病学特征分析[J].中国肺癌杂志,2024,27(12):911-918,8.基金项目
本研究受国家自然科学基金(No.82360562)、云南省科技厅科技计划项目(No.202405AS350015)和云南省"高层次人才培养支持计划"(No.YNWR-MY-2020-045)资助 This study was supported by the grants from National Natural Science Foundation of China(No.82360562)(to Yunchao HUANG),Science and Technology Plan Project of Yunnan Provincial Science and Technology Department(No.202405AS350015)(to Guangqiang ZHAO)and Yunnan Province"High-level Talent Training Support Plan"(No.YNWR-MY-2020-045)(to Guangqiang ZHAO). （No.82360562）
