摘要
Abstract
Mucosa-associated lymphoid tissue(MALT)lymphoma is the most common primary pulmonary lym-phoma,which is an indolent B-cell lymphoma thought to originate from marginal zone B cells.Its pathophysiology is closely related to chronic antigenic stimulation,regardless of whether the antigens are auto-antigens or of microbial origin.Due to its nonspecific clinical presentation and low prevalence,pulmonary MALT lymphoma is often misdiagnosed.The disease is slow-growing,and different treatments have shown good efficacy,but its optimal treatment is somewhat controversial.This paper reviews the epidemiology,pathogenesis,clinical manifestations,computed tomography(CT)features,pathological diagnosis,treatment and prognosis of pulmonary MALT lymphoma,providing reference for clinicians to further understanding of the disease.关键词
黏膜相关淋巴组织淋巴瘤/肺原发性淋巴瘤/NF-κB信号通路/利妥昔单抗/抗生素Key words
Mucosa-associated lymphoid tissue lymphoma/Primary pulmonary lymphoma/NF-κB signal pathway/Rituximab/Anti-bacterial agents