摘要
Abstract
Objective To investigate the distribution of pathogenic bacteria and risk factors of death of ascites in patients with abdominal infection caused by colon perforation.Methods A total of 62 patients with abdominal infection caused by colon perforation admitted to our hospital from October 2020 to Octo-ber 2023 were selected and ascites of all patients were collected for pathogen identification.The clinical data and laboratory examination indicators of all patients were collected,with discharge time as the end point of this observation.According to the prognosis,the patients who died in hospital were classified as the death group and and the patients who survived were set as the survival group(those who were cured or those who were stable and discharged successfully).Multivariate Logistic regression was used to analyze the rele-vant risk factors of death in patients with abdominal infection caused by colon perforation.Results A to-tal of 114 strains of pathogenic bacteria were isolated from the ascite specimens of 62 patients with abdomi-nal infection caused by colon perforation,including 74 strains of Gram-negative bacteria,accounting for 64.91％(74/114),32 strains of Gram-positive bacteria,accounting for 28.07％(32/114),and 8 strains of fungi,accounting for 7.02％(8/114).The acute physiology and chronic health evaluation Ⅱ(APACHEⅡ),sequential organ failure assessment(SOFA),C-reactive protein(CRP),procalcitonin(PCT),white blood cell count(WBC),and red blood cell distribution width(RDW)levels in the death group were higher than those in the survival group(P＜0.05).The results of multi-factor Logistic regression analysis showed that APACHE Ⅱ,SOFA,CRP,PCT,WBC and RDW were all risk factors for in-hospital death in patients with abdominal infection caused by colon perforation(P＜0.05).Conclusion Gram-negative bacteria are the main pathogens of ascites in patients with abdominal infection caused by colon perforation.The in-hospital death is closely related to APACHE Ⅱ,SOFA,CRP,PCT,WBC and RDW.关键词
结肠穿孔/腹腔感染/腹水/病原菌/死亡因素Key words
Colon perforation/Abdominal infection/Ascites/Pathogenic bacteria/Risk factors of death
