非侵入性脑刺激在阿尔茨海默病中应用的文献计量分析OA北大核心

Objective To analyze the research hotspot and future trend of non-invasive brain stimulation(NIBS)in Alzheimer's dis-ease. Methods Relevant literature on application of NIBS in Alzheimer's disease from January,2014 to October,2024 was re-trieved from the Web of Science Core Collection database.CiteSpace 6.4.R1 was used to perform a bibliometric analysis and to create knowledge maps,including annual publication volume,countries,institutions,authors,key-words and co-cited references. Results A total of 731 articles were included,showing an increasing trend in annual publication volume.The United States was the leading country in publication volume,Harvard University was the most productive institution,and Giacomo Koch was the most prolific author.Brain Stimulation was the most frequently cited journal.Highly focused keywords included cognitive impairment,memory,dementia,transcranial magnetic stimulation and tran-scranial direct current stimulation.Bursting keywords in the past two years included transcranial alternating cur-rent stimulation,functional magnetic resonance imaging,brain-derived neurotrophic factor and oxidative stress. Conclusion Research interest in NIBS within the field of Alzheimer's disease has been steadily increasing.The research hotspots include the effect and mechanism of NIBS on cognitive function and the impact of stimulating different brain regions on cognitive outcome.Future research may focus on integrating NIBS with techniques such as func-tional magnetic resonance imaging to achieve individualized and precise stimulation.