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CD200-CD200R通路在炎症相关性疾病中的研究进展

丁子玲 樊毫军 郭小芹 吕琪

中国免疫学杂志2025,Vol.41Issue(2):451-455,5.
中国免疫学杂志2025,Vol.41Issue(2):451-455,5.DOI:10.3969/j.issn.1000-484X.2025.02.033

CD200-CD200R通路在炎症相关性疾病中的研究进展

Recent advances of CD200-CD200R pathway in inflammatory diseases

丁子玲 1樊毫军 1郭小芹 1吕琪1

作者信息

  • 1. 天津大学应急医学研究院,天津 300072
  • 折叠

摘要

Abstract

Many kinds of diseases are accompanied by inflammatory response owing to abnormal immune system functions.It is necessary to take effective measures to dampen inflammatory and reshape microenvironment of local tissue.CD200-CD200R has been proved as an immune checkpoint signaling pathway to exert immunomodulatory effects on a variety of inflammatory diseases caused by multiple body parts,such as central nervous system,female reproductive system,gynecology,eyes,lungs,intestines and virus intrusion.There is also great potential in areas including clinical diagnostic markers,novel treatments and biomaterials.Therefore,it is of great significance to explore regulatory mechanism and proper uses of CD200-CD200R signaling pathway.

关键词

CD200/CD200受体/炎症/免疫调控

Key words

CD200/CD200R/Inflammation/Immune modulation

分类

医药卫生

引用本文复制引用

丁子玲,樊毫军,郭小芹,吕琪..CD200-CD200R通路在炎症相关性疾病中的研究进展[J].中国免疫学杂志,2025,41(2):451-455,5.

基金项目

国家自然科学基金面上项目(81971878). (81971878)

中国免疫学杂志

OA北大核心

1000-484X

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