中国免疫学杂志2025,Vol.41Issue(2):451-455,5.DOI:10.3969/j.issn.1000-484X.2025.02.033
CD200-CD200R通路在炎症相关性疾病中的研究进展
Recent advances of CD200-CD200R pathway in inflammatory diseases
摘要
Abstract
Many kinds of diseases are accompanied by inflammatory response owing to abnormal immune system functions.It is necessary to take effective measures to dampen inflammatory and reshape microenvironment of local tissue.CD200-CD200R has been proved as an immune checkpoint signaling pathway to exert immunomodulatory effects on a variety of inflammatory diseases caused by multiple body parts,such as central nervous system,female reproductive system,gynecology,eyes,lungs,intestines and virus intrusion.There is also great potential in areas including clinical diagnostic markers,novel treatments and biomaterials.Therefore,it is of great significance to explore regulatory mechanism and proper uses of CD200-CD200R signaling pathway.关键词
CD200/CD200受体/炎症/免疫调控Key words
CD200/CD200R/Inflammation/Immune modulation分类
医药卫生引用本文复制引用
丁子玲,樊毫军,郭小芹,吕琪..CD200-CD200R通路在炎症相关性疾病中的研究进展[J].中国免疫学杂志,2025,41(2):451-455,5.基金项目
国家自然科学基金面上项目(81971878). (81971878)