中国免疫学杂志2025，Vol.41Issue(2)：503-509,7.DOI:10.3969/j.issn.1000-484X.2025.02.042
白癜风免疫发病机制的研究进展
Research progress on immune pathogenesis of vitiligo
摘要
Abstract
Vitiligo is a depigmentation skin disease caused by the progressive destruction of autologous epidermal melano-cytes.However,the mechanism of melanocyte dysfunction and death is unclear.It is worth noting that most melanocyte deaths in patients with vitiligo are directly caused by autoimmune response.There are many immune related cell molecules in the body,such as CD8+T cells,IFN-γ and inflammatory cytokines all play a role in the pathogenesis of vitiligo.To clarify the effects of body immunity,cytokines and autoantibodies on the normal function of melanocyte and their role in the condition of vitiligo can provide a basis for finding the treatment of vitiligo.关键词
白癜风/发病机制/细胞免疫/体液免疫Key words
Vitiligo/Pathogenesis/Cellular immunity/Humoral immunity分类
医药卫生引用本文复制引用
李锴骁,胡雯,康晓静..白癜风免疫发病机制的研究进展[J].中国免疫学杂志,2025,41(2):503-509,7.基金项目
国家自然科学基金(82173406). （82173406）
