中国医药科学2025,Vol.15Issue(1):31-34,4.DOI:10.20116/j.issn2095-0616.2025.01.08
抗性淀粉影响帕金森病可能作用机制的研究进展
Research progress on the possible function mechanism of resistant starch impacting Parkinson's disease
摘要
Abstract
Parkinson's disease(PD)is the second largest neurodegenerative disease,and it has become one of the central nervous system diseases that pose a major social problem and economic threat.However,because its pathogenesis is not completely clear,there is a lack of drugs to prevent the development of the disease and cure PD in clinic.With people's increasing attention to health,a brand-new diet therapy is being constructed,which is based on increasing the intake of resistant starch(RS),thus changing the intestinal microflora,leading to the increase of short-chain fatty acids produced by microorganisms and stimulating intestinal cells to secrete glucagon-like peptide-1(GLP-1).The possible function mechanism of RS is comprehensively expounded in improving PD symptoms in this paper,and its application prospect is envisioned in the prevention and treatment of PD in the future.关键词
帕金森病/抗性淀粉/短链脂肪酸/胰高血糖素样肽1Key words
Parkinson's disease/Resistant starch/Short-chain fatty acids/Glucagon-like peptide-1分类
医药卫生引用本文复制引用
李阳,陈江瑛..抗性淀粉影响帕金森病可能作用机制的研究进展[J].中国医药科学,2025,15(1):31-34,4.基金项目
广东省广州市科技计划项目(2023A03J0575). (2023A03J0575)