基于孕早期多维度指标的各年龄段妊娠糖尿病风险因素分析OA

Objective Based on multidimensional clinical information of medical history,physical examination and laboratory tests obtained from prenatal checkups during early pregnancy,to explore the risk factors of gestational diabetes mellitus(GDM)in early pregnancy using logistic regression analysis and to promote precise prevention and control.Methods Clinical information of 1205 pregnant women in early pregnancy in Xiamen Maternal and Child Health Hospital from January 2019 to January 2021 was retrospectively analyzed,including age,pre-pregnancy weight and height,education level,gravidity and parity history,abdominal circumference,alanine aminotransferase,mean arterial pressure(MAP),history of GDM,and family history of diabetes mellitus.Results GDM was diagnosed by oral glucose tolerance test at 24-28 weeks of pregnancy in 280 cases with a prevalence of 23.24%.Logistic regression analysis revealed that advanced age,high pre-pregnancy body mass index(BMI),history of GDM and high MAP values were risk factors for GDM in early pregnancy in the overall population(P＜0.05).Only history of GDM in pregnant women＜30 years of age was significantly associated with GDM in early pregnancy.High pre-pregnancy BMI,history of GDM and high value of MAP in pregnant women 30-35 years of age were risk factors for GDM in early pregnancy.High pre-pregnancy BMI,history of GDM and family history of diabetes in pregnant women＞35 years of age were risk factors for GDM in early pregnancy(P＜0.05).Conclusion The distribution characteristics of risk factors for GDM in early pregnancy are different in various age groups.Precise prevention and control,and stratified management should be carried out in clinical practice to improve pregnancy outcomes and promote maternal and infant health.