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Oxidative stress in diabetes mellitus and its complications:From pathophysiology to therapeutic strategies

Xingyu Chen Na Xie Lixiang Feng Yujing Huang Yuyao Wu Huili Zhu Jing Tang Yuanyuan Zhang

中华医学杂志（英文版）2025，Vol.138Issue(1)：15-27,13.

中华医学杂志（英文版）2025，Vol.138Issue(1)：15-27,13.DOI:10.1097/CM9.0000000000003230

Oxidative stress in diabetes mellitus and its complications:From pathophysiology to therapeutic strategies

Xingyu Chen ¹Na Xie ²Lixiang Feng ²Yujing Huang ²Yuyao Wu ³Huili Zhu ⁴Jing Tang ¹Yuanyuan Zhang⁵

作者信息

1. Department of Radiology,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,China
2. Sichuan International Science and Technology Center for Stress Medicine,West China School of Basic Medical Sciences and Forensic Medicine and State Key Laboratory of Biotherapy,Sichuan University,Chengdu,Sichuan 610041,China
3. Faculty of Medicine,Macau University of Science and Technology,Avenida Wai Long,Macao 999078,China
4. Department of Reproductive Medicine,Key Laboratory of Birth Defects and Related Diseases of Women and Children of Ministry of Education,West China Second University Hospi-tal of Sichuan University,Chengdu,Sichuan 610041,China
5. Department of Pharmacology,Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province,Sichuan Research Center for Drug Precision Industrial Technology,West China School of Pharmacy,Sichuan University,Chengdu,Sichuan 610041,China
折叠

摘要

关键词

Oxidative stress/Diabetes mellitus/Diabetes complications/Redox regulation/Beta cell dysfunction/Insulin resistance/Systemic inflammation/Redox signaling

Key words

Oxidative stress/Diabetes mellitus/Diabetes complications/Redox regulation/Beta cell dysfunction/Insulin resistance/Systemic inflammation/Redox signaling

引用本文复制引用

Xingyu Chen,Na Xie,Lixiang Feng,Yujing Huang,Yuyao Wu,Huili Zhu,Jing Tang,Yuanyuan Zhang..Oxidative stress in diabetes mellitus and its complications:From pathophysiology to therapeutic strategies[J].中华医学杂志（英文版）,2025,138(1):15-27,13.

基金项目

This work was supported by grants from the National Key R&D Program of China(Nos.2023YFC3402100 and 2020YFA0509400),the Guangdong Basic and Applied Basic Research Foundation(No.2019B030302012),the National Natural Science Foundation of China(Nos.81821002,82130082,82341004,82170844,and 82270613),the 1.3.5 project for disciplines of excel-lence,West China Hospital,Sichuan University(No.ZYGD22007 and ZYJC21004),and the Science and Technology Support Program of Sichuan Province(Nos.2023NSFSC1878,2021YFG0137,2022YFH0045,and 2022YFH0102). （Nos.2023YFC3402100 and 2020YFA0509400）

中华医学杂志（英文版）

ISSN：0366-6999

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