中国中老年人衰弱与可能肌少症共病的潜在危险因素研究OA北大核心CSTPCD

Objective To analyze the comorbidity influencing factors of frailty and possible sarcopenia among middle-aged and elderly Chinese adults. Methods Frailty index (FI) was applied to evaluate frailty status,grip strength and repetitive sitting-up time was applied to determine possible sarcopenia. Data used in this study was from the China Health and Retirement Longitudinal Study ( CHARLS) in 2011-2015. Multiple Logistic regression analysis was conducted to explore the influencing factors of comorbidity of frailty and possible sarcopenia. Results The results of multivariate Logistic regression analysis showed that for those aged<60 years,the rate of comorbidity was higher in education level of primary school and below (OR=2. 42,95％ CI:1. 24-4. 74),with history of falls (OR=3. 46,95％ CI:1. 79-6. 68). Results also showed that drinking habits (OR=0. 34,95％ CI:0. 12-0. 95) were protective for comorbidity.Among those aged ≥60 years,the rate of comorbidity was higher in those of average (OR=1. 92,95％ CI:1. 10-3. 33) or unsatisfied (OR=3. 80,95％ CI:2. 07-6. 97) with life,with history of falls (OR=2. 11,95％ CI:1. 43-3. 10),waist-to-height ratio>0. 5 (OR=2. 12,95％ CI:1. 26-3. 56),with depressed mood (OR=3. 07,95％ CI:2. 00-4. 71). Drinking habits (OR=0. 54,95％ CI:0. 34-0. 87) were protective for comorbidity. Conclusion Among people aged 60 years and older,low life satisfaction,history of falls,central obesity,and depressed mood may be the high risks for comorbidity of frailty and possible sarcopenia. Early interventions for potentially at-risk populations can be taken to slow the progression of the disease.