中山大学学报（医学科学版）2025，Vol.46Issue(1)：30-40,11.
呼出气挥发性有机化合物研究进展
Research Progress of Exhaled Volatile Organic Compounds
摘要
Abstract
Human exhaled breath is rich in volatile organic compounds(VOCs)with thousands of varieties.In addition to VOCs inhaled from external air,the vast majority of VOCs come from human metabolism and metabolism of the internal microorganisms.Therefore,exhaled VOCs carry abundant information about the human body,which works as"fingerprint"of an individual's exhalation pointing to the underlying metabolic status,making VOCs an ideal tool for health monitoring and disease diagnosis.In recent years,a large number of studies on disease and exhaled VOCs have shown valuable results.Many diseases in the human body are closely related to oxidative stress reaction which also produces plentiful VOCs discharged through the lungs,offering a new window for monitoring diseases.In the future,the use of exhaled VOCs analysis to detect and diagnose infectious diseases,metabolic diseases and tumors may become a new trend.This paper presents a review on VOCs in terms of concept,collection,detection,clinical application,and the relationship between exhaled VOCs and diseases.关键词
呼出气挥发性有机化合物/肿瘤/哮喘/慢性阻塞性肺疾病/感染Key words
exhaled volatile organic compounds/tumor/asthma/chronic obstructive pulmonary disease/infection分类
临床医学引用本文复制引用
王斌,冯艺..呼出气挥发性有机化合物研究进展[J].中山大学学报（医学科学版）,2025,46(1):30-40,11.基金项目
北京市临床重点专科卓越项目[京卫医(2021)135号] （2021）
