中山大学学报(医学科学版)2025,Vol.46Issue(1):41-49,9.
干细胞移植治疗卒中后认知障碍的相关研究进展
Research Progress of Stem Cells Transplantation in Treatment of Cognitive Impairment After Stroke
摘要
Abstract
Stroke is a common acute cerebrovascular disease.Post-stroke cognitive impairment(PSCI)is one of the most common complications of stroke,which seriously affects the quality of life and physical health of patients.As a cutting-edge medical therapy,stem cells transplantation has great potential in the treatment of PSCI by reducing inflammation,promoting axon regeneration and immune regulation,and has become the focus of current research.However,the relationship between stem cells transplantation and PSCI has not been systematically summarized.Therefore,this paper will briefly summarize the biological functions of different types of stem cells,systematically comb out and summarize the mechanisms of stem cells transplantation in PSCI regulation and its applications in PSCI treatment,providing a deeper understanding and strategy for clinical PSCI management.关键词
干细胞移植/脑卒中/认知功能障碍/间充质干细胞/神经干细胞Key words
stem cells transplantation/stroke/cognitive dysfunction/mesenchymal stem cells/neural stem cells分类
临床医学引用本文复制引用
潘蕊,张铭..干细胞移植治疗卒中后认知障碍的相关研究进展[J].中山大学学报(医学科学版),2025,46(1):41-49,9.基金项目
河南省中医药科学研究专项(20-21ZY1017) (20-21ZY1017)
河南省中医药传承与创新人才工程(仲景工程)-拔尖人才(CZ0325-14) (仲景工程)
河南省中医学"双一流"创建科学研究专项(HSRP-DFCTCM-2023-3-11) (HSRP-DFCTCM-2023-3-11)