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重构本草——桃仁

李坤 王阁 张伟 赵林华 黄晓巍 陈锐

长春中医药大学学报2025,Vol.41Issue(2):136-138,3.
长春中医药大学学报2025,Vol.41Issue(2):136-138,3.DOI:10.13463/j.cnki.cczyy.2025.02.005

重构本草——桃仁

Reconstruction of Chinese materia medica-peach seed

李坤 1王阁 2张伟 3赵林华 4黄晓巍 5陈锐1

作者信息

  • 1. 长春中医药大学,长春 130117
  • 2. 长春中医药大学药学院,长春 130117
  • 3. 中国中医科学院广安门医院代谢病研究所,北京 100053||甘肃中医药大学基础医学院,兰州 730000
  • 4. 中国中医科学院广安门医院代谢病研究所,北京 100053
  • 5. 东北亚中医药研究院,长春 130117
  • 折叠

摘要

Abstract

Through investigation of ancient books and the sorting of modern research achievements of traditional Chinese medicine,combined with the understanding and application experience of famous experts and scholars in desciplinary fields such as traditional Chinese medicine clinical medicine and science of Chinese materia medica,it is concluded that peach seed mainly has the effects of promoting blood circulation for removing blood stasis,clearing intestine and facitating feces excretion,and relieving cough and asthma.The symptom targets are amenorrhea and constipation.Modern pharmacological studies have found that peach seed and its active ingredients have effects of inhibiting thrombosis,cardiovascular protection,anti-tumor,anti-inflammatory,clearing intestine and facitating feces excretion,and protecting the respiratory system.Hydrocyanic acid,a metabolite of amygdalin found in the peach seed coat,has certain toxicity and should usually be used without skin in clinical practice;And using roasted and stir-fried peach seed can reduce toxicity and make the active ingredients more easily extracted through decoction.The clinical dosage is 3-30g.When taken orally,it should be used based on syndrome differentiation according to different diseases or different stages of the same disease,and the construction of dose-effect relationship between the dosage of peach seed and the symptom target and biochemical indicator target should be explored actively.

关键词

桃仁/症靶/重构本草/临床回归

Key words

peach seed/symptom target/reconstruction of Chinese materia medica/clinical verification

分类

医药卫生

引用本文复制引用

李坤,王阁,张伟,赵林华,黄晓巍,陈锐..重构本草——桃仁[J].长春中医药大学学报,2025,41(2):136-138,3.

基金项目

国家自然基金委-中国科学院联合项目资助中西医结合创新范式战略研究(XK2023SMC003) (XK2023SMC003)

长春中医药大学学报

2095-6258

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