辐射研究与辐射工艺学报2025,Vol.43Issue(1):49-55,7.DOI:10.11889/j.1000-3436.2024-0060
铅门自动跟随技术在多发性脑转移瘤容积调强计划中的剂量学研究
Jaw automated tracking techniques in volumetric modulated arc therapy plans for multiple brain metastases
摘要
Abstract
This study investigated the dosimetric results and gamma passing rates of jaw-automated tracking(JAT)techniques in volumetric modulated arc therapy(VMAT)plans for patients with multiple brain metastases.From August 2017 to March 2020,15 patients with multiple brain metastases were enrolled in this study at Yunyang People's Hospital.For each patient,a VMAT plan was created using both the JAT and jaw manual fixed(JMF)techniques.Plan quality was evaluated by comparing the conformity index(CI),homogeneity index(HI),and dose to organs at risk,including the whole brain and brainstem.Evaluation indicators and dose distributions were compared between the JAT and JMF groups.The results indicated that the JAT plans demonstrated better HI(0.060 vs.0.080,p<0.05)and a lower mean dose for the whole brain(853.8 cGy vs.893.4 cGy,p<0.05).Additionally,the JAT plans exhibited reduced dose exposure in V10(56.1%vs.60.2%,p<0.05)and V20(28.5%vs.29.5%,p<0.05)compared to the JMF plans.No significant differences were observed between the two groups in terms of CI and maximum dose to the brainstem.In conclusion,VMAT plans utilizing JAT techniques can enhance HI and decrease dose exposure to the entire brain.关键词
多发脑转移瘤/容积调强计划/铅门自动跟随/铅门手动固定Key words
Multiple brain metastases/Volumetric modulated arc therapy/Jaw automated tracking(JAT)/Jaw manual fixed(JMF)分类
医药卫生引用本文复制引用
金建华,李明,袁波,李中亚..铅门自动跟随技术在多发性脑转移瘤容积调强计划中的剂量学研究[J].辐射研究与辐射工艺学报,2025,43(1):49-55,7.基金项目
南通市科技局项目(MSZ20209)资助 Supported by Nantong Science and Technology Bureau Project(MSZ20209) (MSZ20209)