国际护理科学（英文）2025，Vol.12Issue(1)：51-58,8.DOI:10.1016/j.ijnss.2024.12.007
接受手术和化疗的乳腺癌患者自我报告结局的潜在类别分析
Identification of subgroups of self-reported outcomes among breast cancer patients undergoing surgery and chemotherapy:A cross-sectional study
摘要
Abstract
Objectives:To identify the subgroups of self-reported outcomes and associated factors among breast cancer patients undergoing surgery and chemotherapy. Methods:A cross-sectional study was conducted between January and November 2021.We recruited patients from two tertiary hospitals in Shanghai,China,using convenience sampling during their hos-pitalization.Patients were assessed using a questionnaire that included sociodemographic and clinical characteristics,the Patient Reported Outcomes Measurement Information System profile-29(PROMIS-29),and the PROMIS-cognitive function short form 4a.Latent class analysis was performed to examine possible classes regarding self-reported outcomes.Multiple logistic regression analysis was used to determine the associated factors.Analysis of variance(ANOVA)was conducted for symptoms across the different classes. Results:A total of 640 patients participated in this study.The findings revealed three subgroups in terms of self-reported outcomes among breast cancer patients undergoing surgery and chemotherapy:low physical-social-cognitive function,high physical-low cognitive function,and high physical-social-cognitive function.Multivariable logistic regression analysis showed that age(≥ 60 years old),meno-pause,the third chemotherapy cycle,undergoing simple mastectomy and breast reconstruction,duration of disease 3-12 months,stage Ⅲ/IV cancer,and severe pain were associated factors of the functional decline groups.Besides,significant differences in depression and sleep disorders were observed among the three groups. Conclusions:Breast cancer patients receiving surgery and chemotherapy can be divided into three subgroups.Aging,menopause,chemotherapy cycle,surgery type,duration and stage of disease,and severe pain affected the functional decline groups.Consequently,healthcare professionals should make tailored interventions to address the specific functional rehabilitation and symptom relief needs.关键词
乳腺癌/潜在类别分析/功能/手术/化疗Key words
Breast neoplasms/Latent class analysis/Function/Surgery/Chemotherapy引用本文复制引用
倪飞霞,蔡婷婷,周婷婷,袁长蓉..接受手术和化疗的乳腺癌患者自我报告结局的潜在类别分析[J].国际护理科学（英文）,2025,12(1):51-58,8.基金项目
This study was supported by the Hospital-level Nursing Research Project of Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine(xhhlcx2023-017) （xhhlcx2023-017）
the third period of the 14th Five-Year nursing talent project of Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine(Xhlxm014) （Xhlxm014）
the Ministry of Education of Humanities and Social Science Project(23YJC630002)and High-level local university construction project founded by Shanghai Municipal Education Commission. （23YJC630002）
