国际医药卫生导报2025，Vol.31Issue(3)：360-365,6.DOI:10.3760/cma.j.cn441417-20240824-03002
实时三维超声心动图参数对急性心肌梗死患者PCI术后支架内再狭窄的预测价值
Predictive value of real-time 3D echocardiographic parameters for in-stent restenosis after percutaneous coronary intervention in patients with acute myocardial infarction
摘要
Abstract
Objective To assess the value of real-time 3D echocardiographic parameters in predicting in-stent restenosis after percutaneous coronary intervention(PCI)in patients with acute myocardial infarction.Methods This study was a retrospective analysis.The clinical data of 100 patients with acute myocardial infarction who underwent PCI in Hanzhong People's Hospital from July 2019 to January 2022 were collected.The patients were divided into a restenosis group(30 cases)and a non-restenosis group(70 cases)according to in-stent restenosis within 6 months after surgery.The left ventricular function and synchronization parameters were compared between the two groups.Lasso regression modeling was used to screen out the key characteristic variables of restenosis,and the clinical value of the variables was evaluated by the receiver operating characteristic curve(ROC),calibration curve,and decision curve analysis(DCA).Independent sample t test and x2 test were used for statistical analysis.Results The left ventricular end-diastolic volume(LVEDV)in the restenosis group was higher than that in the non-restenosis group[(142.07±28.62)ml vs.(113.83±32.55)ml],but the left ventricular ejection fraction(LVEF),peak ejection rate(PER)/end-diastolic volume(EDV),and peak filling rate(PFR)/EDV were all lower than those in the non-stenosis group[(46.77±4.26)％vs.(49.84±4.26)％,(1.89±0.62)L/s vs.(2.47±0.87)L/s,(1.36±0.45)L/s vs.(1.77±0.68)L/s],with statistically significant differences(t=4.335,-3.312,-3.794,and-3.598,all P＜0.001).The characteristic variables of in-stent restenosis were screened by Lasso regression analysis,and 5 characteristic variables were obtained,including LVEDV,LVEF,Tmsv12-Dif/R-R,Tmsv12-SD/R-R,and Tmsv16-SD/R-R.The risk score of the restenosis group was lower than that of the non-restenosis group[(0.02±0.99)points vs.(1.54±1.07)points,t=6.653,P＜0.001],and the area under the curve of the Lasso risk score was 0.866.Conclusions In this study,we assessed left ventricular function and synchronization by real-time 3D echocardiography and LASSO regression in patients after PCI,screening key characteristic variables to predict restenosis risk.关键词
急性心肌梗死/经皮冠状动脉介入治疗/实时三维超声心动图/支架内再狭窄/预测Key words
Acute myocardial infarction/Percutaneous coronary intervention/Real-time 3D echocardiography/In-stent restenosis/Prediction引用本文复制引用
黄新亮,杜亚坤,任红梅..实时三维超声心动图参数对急性心肌梗死患者PCI术后支架内再狭窄的预测价值[J].国际医药卫生导报,2025,31(3):360-365,6.基金项目
国家自然科学基金(81760070) National Natural Science Foundation of China(81760070) （81760070）
