湖南中医药大学学报2025，Vol.45Issue(1)：80-85,6.DOI:10.3969/j.issn.1674-070X.2025.01.011
子午流注纳甲法联合揿针治疗特发性面神经麻痹的临床疗效观察
Clinical observation on the efficacy of midnight-noon ebb-flow day-stem point selection combined with thumbtack needle therapy for idiopathic facial paralysis
摘要
Abstract
Objective To explore the clinical efficacy of midnight-noon ebb-flow day-stem point selection combined with thumbtack needle therapy in treating idiopathic facial paralysis(IFP).Methods Ninety-six patients with IFP admitted to the Department of Acupuncture and Physical Therapy of Zhangjiagang Fifth People's Hospital from January 2023 to December 2023 were selected as the study subjects.They were divided into control group(n=32),treatment group A(n=32),and treatment group B(n=32)according to the random number table method.The control group was treated with conventional acupoint selection based on pattern identification,the treatment group A was treated with conventional acupoint selection based on pattern identification and midnight-noon ebb-flow day-stem method.The treatment group B was treated with conventional acupoint selection based on pattern identification and midnight-noon ebb-flow day-stem method combined with thumbtack needle therapy.All three groups were treated continuously for four weeks.The clinical efficacy,Chinese medicine pattern scores,neurological function[assessed using the Facial Disability Index(FDI)scale and the Sunnybrook facial nerve rating system],neurotrophic factors[nerve growth factor(NGF),glial cell derived neurotrophic factor(GDNF)],hemodynamic parameters[peak systolic velocity(PSV),resistance index(RI)],and adverse reactions were compared among the three groups.Results The total effective rate of treatment group B was higher than that of treatment group A and the control group(P＜0.05).After treatment,the Chinese medicine pattern scores(including scores for facial asymmetry,facial stiffness and numbness,ptosis or incomplete eyelid closure)in treatment group B were lower than those in treatment group A and the control group(P＜0.05).The scores for facial disability index physical functions(FDIP),facial disability index social functions(FDIS),and Sunnybrook in treatment group B were higher than those in treatment group A and the control group(P＜0.05).After treatment,the serum levels of NGF and GDNF in treatment group B were higher than those in treatment group A and the control group(P＜0.05).The PSV level in treatment group B was higher than that in treatment group A and the control group(P＜0.05),while the RI level was lower(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions among the three groups(P＞0.05).Conclusion Midnight-noon ebb-flow day-stem point selection combined with thumbtack needle therapy shows significant efficacy in patients with IFP,effectively improving neurological function,promoting the NGF and GDNF expressions,and enhancing facial hemodynamics.关键词
特发性面神经麻痹/子午流注纳甲法/揿针/神经功能/神经营养因子/血流动力学Key words
idiopathic facial paralysis/midnight-noon ebb-flow day-stem point selection/thumbtack needle/neural func-tion/neurotrophic factors/hemodynamics分类
医药卫生引用本文复制引用
肖云,蒋胜利,顾焱,周思源,岳露露,陆少武..子午流注纳甲法联合揿针治疗特发性面神经麻痹的临床疗效观察[J].湖南中医药大学学报,2025,45(1):80-85,6.基金项目
张家港市科技计划项目(ZKYL2254). （ZKYL2254）
