结核与肺部疾病杂志2025，Vol.6Issue(1)：1-7,7.DOI:10.19983/j.issn.2096-8493.2024132
便携式睡眠监测对阻塞性睡眠呼吸暂停低通气患者整夜病情评估及心血管疾病风险因素分析
Analysis of all-night evaluation indexes and predictors of cardiovascular risk in patients with obstructive sleep apnea-hypopnea syndrome
摘要
Abstract
Objective:To explore overnight assessment indicators and cardiovascular disease risk predicators of obstructive sleep apnea using portable sleep monitoring.Methods:A retrospective,clinical case analysis was used to screen 192 outpatients and inpatients from May 2019 to July 2020.Physical measurements,blood pressure,past medical history,and biochemical indicators of the patients were recorded.Data of AHI,lowest oxygen saturation,average oxygen saturation,longest apnea duration,longest hypopnea duration,the ratio of overnight oxygen saturation below 90％,the ratio of total apnea time to sleep time,the ratio of total hypopnea time to sleep time and Epworth sleepiness scale were collected for analysis.According to the criteria,152 patients were included for ASCVD risk analysis with China-PAR model,PM indexes that influence ASCVD risk were analyzed.Results:One hundred and seventy-nine patients diagnosed with obstructive sleep apnea-hypopnea syndrome.Among PM monitoring indexes,lowest oxygen saturation(OR=0.84,P=0.002)and longest apnea duration(OR=0.96,P=0.017)were negative corrected to AHI,total apnea time to sleep time ratio(OR=1.89,P＜0.001),total hypopnea time to sleep time ratio(OR=2.23,P＜0.001)were positive corrected to AHI,the others indexes were not statistically corrected to AHI.Statistically significant differences of T90％were found in severe AHI group and the other groups(severe AHI group vs.normal/mild/moderate AHI group:18.8±16.4 vs.0.1±0.5/1.7±5.8/2.9±3.8,F=35.40,P＜0.001).T90％and the ratio of total apnea time to sleep time were associated with 10-year ASCVD risk in obstructive sleep apnea-hypopnea syndrome patients(T90％:OR=1.15,P=0.001;total apnea time to sleep time:OR=1.09,P=0.013).Conclusion:The ratio of overnight oxygen saturation below 90％and total apnea time to test time ratio can be suggested as all-night evaluation indexes and indicator factors for ASCVD risk of obstructive sleep apnea-hypopnea syndrome patients.关键词
睡眠呼吸暂停综合征/监测,便携式/危险性评估/心血管疾病Key words
Sleep apnea syndromes/Monitoring,ambulatory/Risk assessment/Cardiovascular diseases分类
医药卫生引用本文复制引用
曾文美,吴苏龙,刘灼帆,袁茏,陈碧琳,荣艳..便携式睡眠监测对阻塞性睡眠呼吸暂停低通气患者整夜病情评估及心血管疾病风险因素分析[J].结核与肺部疾病杂志,2025,6(1):1-7,7.基金项目
深圳市南山区技术研发和创意设计项目分项(NS2021002 （）
NS2022013) The Technical Research and Development and Creative Design Project sub-funds(NS2021002 （）
NS2022013) （）
