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恶性血液病病人非计划性再入院风险预测模型的构建与验证

崔岩 陈明明 宋振 马跃申 张会娟 吴桂彬 靳兆娜 张倩倩 解文君

全科护理2025,Vol.23Issue(4):616-621,6.
全科护理2025,Vol.23Issue(4):616-621,6.DOI:10.12104/j.issn.1674-4748.2025.04.005

恶性血液病病人非计划性再入院风险预测模型的构建与验证

Development and validation of a risk prediction model for unplanned readmission in patients with hematologic malignancies

崔岩 1陈明明 1宋振 1马跃申 1张会娟 1吴桂彬 1靳兆娜 1张倩倩 1解文君1

作者信息

  • 1. 300020,中国医学科学院血液病医院(中国医学科学院血液学研究所)
  • 折叠

摘要

Abstract

Objective:To explore the risk factors for unplanned readmission in patients with hematologic malignancies and develop a risk prediction model.Methods:Clinical data from 3 241 patients with hematologic malignancies treated at a tertiary grade A hospital in Tianjin between January 1,2017,and December 31,2021,were retrospectively collected.The patients were randomly divided into a modeling group(2,269 cases)and a validation group(972 cases)in a 7∶3 ratio.Univariate and Logistic regression analysis were used to construct the risk prediction model.The Hosmer-Lemeshow test and receiver operating characteristic(ROC)curve were employed to evaluate the model's calibration and discrimination,and a Nomogram was developed.Results:The incidence of unplanned readmission in the modeling group was 14.50%(329/2 269).Logistic regression analysis showed that the risk factors included in the risk prediction model were disease types,Eastern Cooperative Oncology Group Performance Status(ECOG)score,pulmonary infection,central venous catheterization,and comorbidities.The Hosmer-Lemeshow test result of the modeling group was χ2=8.569,P=0.380,and the area under the ROC curve(AUC)was 0.796,the Youden index was 0.454,the sensitivity was 78.70%,and specificity was 66.60%.The Hosmer-Lemeshow test result of the validation group was χ2=3.491,P=0.900,the AUC was 0.771,with an accuracy of 76.23%.Conclusion:The developed risk prediction model demonstrates good performance and may assist clinical nurses in identifying high-risk patients for targeted interventions.

关键词

恶性血液病/非计划性再入院/危险因素/预测模型/护理

Key words

hematologic malignancies/unplanned readmissions/risk factors/prediction model/nursing

引用本文复制引用

崔岩,陈明明,宋振,马跃申,张会娟,吴桂彬,靳兆娜,张倩倩,解文君..恶性血液病病人非计划性再入院风险预测模型的构建与验证[J].全科护理,2025,23(4):616-621,6.

基金项目

天津市护理学会科研项目,编号:tjhlky2022YB02. ()

全科护理

1674-4748

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