首都师范大学学报（自然科学版）2025，Vol.46Issue(1)：40-54,15.DOI:10.19789/j.1004-9398.2025.01.006
Katritzky盐作为氮自由基前体参与的化学反应研究进展
Recent advances in the chemistry of Katritzky salts as nitrogen-centered radical precursors
摘要
Abstract
The radical intermediates play a significant role in a variety of reactions,enabling rapid access to drug molecules,natural products,building blocks and other functional molecules.While the radicals of Katritzky salts can be generated under the catalysis of transition metal,photoredox,etc,which makes the Katritzky salts involving N—N bond be important precursors of generating nitrogen-centered radicals.Here,the brief review has focused on the transformations of nitrogen-centered radical generated from Katritzky salts,reviewing the strategies such as transition-metal catalysis,photoredox catalysis and applications in C—H bond functionalization,difunctionalization of alkenes and alkynes,and other relevant reactions.It is obvious that,Katritzky salts,as important precursors of nitrogen-centered radicals,hold the promise of achieving a variety of radical-based transformations for accessing unexplored chemical space.关键词
Katritzky盐/氮自由基/自由基转化/多种官能团转化Key words
Katritzky salt/nitrogen-centered radical/radical transformations/various functionalization reactions分类
化学化工引用本文复制引用
胡少俊,朱光礼,陈铁根..Katritzky盐作为氮自由基前体参与的化学反应研究进展[J].首都师范大学学报（自然科学版）,2025,46(1):40-54,15.基金项目
上海市自然科学基金面上项目(23ZR1474300) （23ZR1474300）
上海市青年科技启明星计划项目(21QA1411000) （21QA1411000）
中山市社会公益与基础研究项目(2021B2014) （2021B2014）
