世界中西医结合杂志2025，Vol.20Issue(1)：10-15,6.DOI:10.13935/j.cnki.sjzx.250102
下肢丹毒患者中医证型与临床指标的相关性研究
Correlations between Traditional Chinese Medicine Syndromes and Clinical Indica-tors in Patients with Lower Limb Erysipelas
摘要
Abstract
Objective To analyze the correlations between different traditional Chinese medicine(TCM)syn-dromes and clinical indicators in the patients with lower limb erysipelas,providing guidance for clinical diagnosis and treat-ment.Methods A total of 137 patients with lower limb erysipelas hospitalized from June 2009 to June 2023 at the Depart-ment of Sore and Vascular Surgery,Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical Universi-ty were selected.Their electronic medical records were retrospectively collected for analysis of the demographic data,symp-tom data,and laboratory test results.The patients were assigned into three groups based on TCM syndromes.Statistical tests such as t-test,rank sum test,or Chi-square test were performed to analyze each indicator.Multiple logistic regression a-nalysis was performed for indicators with P＜0.05.Results Differences existed in twelve clinical indicators among the three groups of patients with different TCM syndromes(P＜0.05).The patients with the syndrome of heat accumulation in blood had higher absolute neutrophil count(day 7)and alanine aminotransferase level(day 0),which influenced the TCM syndrome(P＜0.05).The patients with the syndrome of excessive heat toxin congestion had lower white blood cell count(day 7),percentage of neutrophils(day 7),and erythrocyte sedimentation rate(day 14)and higher alanine aminotrans-ferase level(day 0),which affected the TCM syndrome(P＜0.05).The skin temperature score before treatment was higher in the patients with the syndrome of heat accumulation in blood.The pain score before treatment was higher in the patients with the syndrome of excessive heat toxin congestion,while it was lower in the patients with the syndrome of stasis in merid-ians and collaterals,which meant that this factor impacted the TCM syndrome(P＜0.05).Conclusion The TCM syn-dromes of patients with lower limb erysipelas exhibits correlations with inflammation and liver function indicators.Among these indicators,the absolute neutrophil count,percentage of neutrophils,total white blood cell count,alanine aminotrans-ferase level,pain score upon admission,and skin temperature score can serve as key clinical indicators for differentiating TCM syndromes in the patients with lower limb erysipelas.关键词
下肢丹毒/证型/临床指标/相关性Key words
Lower Limb Erysipelas/Traditional Chinese Medicine Syndrome/Clinical Indicators/Correlation分类
医药卫生引用本文复制引用
于芳宁,张博,蔺莉,马逸朝,陈昱坤,顾天贺,徐旭英..下肢丹毒患者中医证型与临床指标的相关性研究[J].世界中西医结合杂志,2025,20(1):10-15,6.基金项目
国家自然科学基金(82174388) （82174388）
北京市百千万人才工程(2019A30) （2019A30）
北京市医管中心人才培养计划"登峰"项目(DFL20220801) （DFL20220801）
第五批全国中医临床优秀人才研修项目(国中医药办人教函[2021]271号) （国中医药办人教函[2021]271号）
