兽类学报2025，Vol.45Issue(1)：86-95,10.DOI:10.16829/j.slxb.150791
麋鹿角脱落和再生与血液激素含量的关系
Relationship between the level of blood hormones and the shedding and regeneration of male Père David's deer(Elaphurus davidianus)antlers
摘要
Abstract
The antlers of male Père David's deer(Elaphurus davidianus)were shed during the winter solstice,and hor-mones play a crucial role in the regeneration of antler cartilage.This study collected blood samples from male Père Da-vid's deer(Elaphurus davidianus)to measure hormone levels,comparing pre-winter solstice(November-December)and post-winter solstice(January-March)periods,as well as analyzing the fluctuations during the antler growth period(Win-ter Solstice-Start of Insects Awakening,December to March of the following year).The aim is to provide further evi-dence for the relationship between antler cartilage regeneration and hormone levels.Results showed that blood estradiol(E2),testosterone(T),growth hormone(GH),insulin-like growth factor-1(IGF-1),and melatonin(MT)levels exhibited significant annual rhythmic changes(F11,486=3.98,n=507,P=0.004).Blood parathyroid hormone(PTH)levels showed synchronous monthly changes with antler ossification(F11,486=1.72,n=507,P=0.081).After the winter sol-stice,blood E2,GH,T,and PTH levels in deer antlers began to gradually increase,while IGF-1 levels increased later.Throughout the antler growth period,blood IGF-1,MT,GH,T,and E2 levels were significantly positively correlated with the regeneration speed of deer antlers,while blood PTH levels were significantly positively correlated with antler weight gain.During the Major Snow solar term(early December),the content of MT,GH,and IGF-1 in the blood began to increase,and the content of E2 and T was at the second peak of the year,which was extremely significantly different from the content of E2 and T during the breeding season of male deer(F7,152=4.08,n=160,P=0.003).During the win-ter solstice,the slow growth phase Ⅲ and the rapid growth phase Ⅳ of the antlers,the content of MT,GH,and IGF-1 in the blood of deer antlers increased sharply(F3,80=4.69,n=84,P=0.002);the content of E2 first decreased and then in-creased,with significant differences(F3,80=3.14,n=84,P=0.045),while the content of T decreased from(0.696 9±0.09)ng/mL(n=84)to(0.664 7±0.06)ng/mL(n=84),with no significant difference(F3,80=5.79,P=0.178).After the Rainwater solar term(late February),during the stagnation and ossification phase V of antler growth,the content of GH in the blood decreased significantly,with significant differences(F3,80=3.25,n=84,P=0.037),while the content of E2 and T continued to increase.PTH levels continued to rise before shedding and throughout the antler growth peri-od,increasing from(11.78±2.54)pg/mL(n=22)during the Major Snow solar term to(69.23±7.89)pg/mL(n=22)during the Vernal Equinox solar term,with extremely significant differences(F1,20=4.44,P=0.001).In conclusion,E2,MT,GH,IGF-1,T,and PTH are all involved in the entire process of winter antler regeneration in deer antlers.Low phys-iological concentrations of melatonin and testosterone during the winter solstice are directly related to antler shedding.This study can provide a basis for improving the breeding conditions of male deer in winter and contribute to research on the regulation of cartilage proliferation by hormones and the diverse mechanisms of antler regeneration.关键词
雌二醇/睾酮/胰岛素样生长因子1/褪黑素/血液甲状旁腺激素/麋鹿角脱落和再生Key words
Estradiol/Testosterone/Insulin-like growth factor 1/Melatonin/Blood parathyroid hormone/Antler shed-ding and regeneration分类
生物科学引用本文复制引用
孟庆辉,钟震宇,孟秀祥,张付贤,柏超,张成林,夏志强,单云芳,李俊芳,贺永惠,崔艳红,胡华刚,肖璇,白加德..麋鹿角脱落和再生与血液激素含量的关系[J].兽类学报,2025,45(1):86-95,10.基金项目
北京自然科学基金(5212003,5252004) （5212003,5252004）
北京动物园圈养野生动物技术北京市重点实验室开放课题(ZDK202101) （ZDK202101）
