色谱2025，Vol.43Issue(2)：120-130,11.DOI:10.3724/SP.J.1123.2024.01002
基于共价有机框架材料的固相微萃取研究进展
Research advance of solid-phase microextraction based on covalent organic framework materials
摘要
Abstract
Solid-phase microextraction(SPME)is a fast and simple sample preparation tech-nique that enables the enrichment of analytes,and it is used in combination with other detec-tion techniques to provide accurate and sensitive analytical methods.SPME is widely used in environmental monitoring,food safety,life analysis,biomedicine,and other applications.The extractive coating is the core of the SPME technique,and the properties of the extractive coat-ing greatly influence extraction selectivity and efficiency,as well as the enrichment effect.Therefore,the development of new and efficient extractive coating materials remains a hot top-ic in the analytical chemistry and sample preparation fields.Covalent organic frameworks(COFs)are a kind of porous crystalline network polymer materials formed by covalent bonds.Owing to the advantages of large specific surface area,high porosity,good stability,high des-ignability,simple synthesis and post-modification,etc.,it has been widely used in gas adsorp-tion,catalysis,sensing and drug delivery.In recent years,COFs have attracted much attention in the field of sample preparation.A variety of novel COF-based SPME materials had been de-veloped for extracting and enriching various types of analytes through π-π interaction,hydro-philic/hydrophobic interaction,electrostatic adsorption,and hydrogen-bonding,as well as pore effects.In this paper,the research advances of COFs for using in fiber-,in tube-,and membrane-based SPME over the past three years were discussed.Fiber surfaces had been mod-ified with functionalized COFs or COF-hybrid materials for use in SPME through physical coat-ing,in-situ growth,and chemical-bonding approaches.The combination of SPME fiber and chromatographic analysis can be used to detect a variety of analytes such as polycyclic aromatic hydrocarbons,phthalates,polychlorinated biphenyls,and pesticides in environmental and food samples,with good enrichment effects,wide linear ranges,and high sensitivity.Based on in tube-SPME,COFs-based monolithic column and fiber-filled tube as the extraction tubes were combined with high performance liquid chromatography online to develop highly sensitive de-tection methods for synthetic phenolic antioxidants and bisphenol compounds,respectively.In addition,COFs had also been used in membrane SPME technique,showing high efficiency in the extraction of trace polychlorinated biphenyls in environmental water.Finally,the develop-ment trends of COFs in the field of SPME was prospected.关键词
共价有机框架/固相微萃取/色谱分析/环境分析/食品分析/生物分析/综述Key words
covalent organic frameworks(COFs)/solid-phase microextraction(SPME)/chromatographic analysis/environmental analysis/food analysis/bioanalysis/review分类
化学化工引用本文复制引用
程颖超,高祎阳,李小敏,陈鲁玉,杜芳,郭洁,孟弋童,孙敏,冯娟娟..基于共价有机框架材料的固相微萃取研究进展[J].色谱,2025,43(2):120-130,11.基金项目
2023年山东省大学生创新创业训练计划项目(202310427292) （202310427292）
山东省自然科学基金(ZR2023MB006,ZR2023MB154) （ZR2023MB006,ZR2023MB154）
国家自然科学基金(21777054,21405061).2023 Shandong College Students Innovation and Entrepreneurship Training Program Project(No.202310427292) （21777054,21405061）
Natural Science Foundation of Shandong Province(Nos.ZR2023MB006,ZR2023MB154) （Nos.ZR2023MB006,ZR2023MB154）
National Natural Science Foundation of China(Nos.21777054,21405061). （Nos.21777054,21405061）
