基础医学教育2025，Vol.27Issue(1)：43-48,6.DOI:10.13754/j.issn2095-1450.2025.01.10
基于学科交叉整合的医学细胞生物学实验开放性教学探索
Exploration on open teaching of medical cell biology experiments based on interdisciplinary integration
摘要
Abstract
In the experimental teaching of medical cell biology in most medical colleges and universities,the students perform mor-phological observation only through tissue sections,and the teaching effect is unsatisfactory due to the single experimental form.Based on the concept of interdisciplinarity,the authors designed a comprehensive teaching experiment of organelle staining and observation,in which cells'structure and function correspond,and students of clinical medicine and basic medicine were recruited to carry out open experiments.The students incubate the cells with drugs carrying fluorophores,use Mitotracker and Lysotracker,two live dye reagents,to stain mitochondria and lysosomes with specific fluorescence,and observe dynamic process of drugs uptake into organelles.Teachers adopted online and offline blended teaching mode and designed three stages of pre-class learning,in-class guidance,and after-class training to create an interdisciplinary experimental teaching course,in which self-learning is highlighted,with teachers'guidance as a supplement,in order to make up for the weaknesses of single content and insufficient training of academic innovative thinking in tradi-tional experimental courses.Based on the interdisciplinarity,this teaching reform aims to help students to better understand the func-tion of organelles,improve autonomous learning ability,and develop experimental skills in scientific research,laying a solid foundation for their future scientific research.关键词
医学细胞生物学/细胞器/荧光染色/实验教学/学科交叉整合/开放性实验Key words
medical cell biology/cell organelles/fluorescent staining/experimental teaching/interdisciplinarity/open experiment分类
生物科学引用本文复制引用
何美娜,张拓..基于学科交叉整合的医学细胞生物学实验开放性教学探索[J].基础医学教育,2025,27(1):43-48,6.基金项目
国家自然科学基金青年基金资助项目(32100913,32100686) （32100913,32100686）
贵州省大学生创新创业训练计划基金资助项目(S202310666092,S202310660101) （S202310666092,S202310660101）
