近红外碳点:开创生物医学应用的新前沿
Near-infrared carbon dots:pioneering emerging frontiers in biomedical applications
摘要
Abstract
Carbon dots(CDs)are fluorescent carbon-based nanomaterials with sizes smal-ler than 10 nm,that are renowned for their exceptional properties,including superior anti-photobleaching,excellent biocompatibility,and minimal toxicity,which have received sig-nificant interest.Near-infrared(NIR)light has emerged as an ideal light source in the biolo-gical field due to its advantages of minimal scattering and absorption,long wavelength emission,increased tissue penetration,and reduced interference from biological back-grounds.CDs with efficient absorption and/or emission characteristics in the NIR spectrum have shown remarkable promise in the biomedical uses.This study provides a comprehens-ive overview of the preparation methods and wavelength modulation strategies for near-in-frared CDs and reviews research progress in their use in the areas of biosensing,bioimaging,and therapy.It also discusses current challenges and clinical prospects,aimed at deepening our understanding of the subject and promoting further advances in this field.关键词
近红外碳点/生物成像/生物传感/治疗/生物医学Key words
Near-infrared carbon dots/Bioimaging/Biosensing/Therapy/Biomedicine分类
化学化工引用本文复制引用
贺倩,杨艳丽,李瑞娇,马丹,张莉芸..近红外碳点:开创生物医学应用的新前沿[J].新型炭材料（中英文）,2025,40(1):131-153,23.基金项目
The authors acknowledge the financial support by Talent Introduction Research Initiation Fund of Shanxi Bethune Hospital(2022RC04),Basic Re-search Program Youth Science Research Project of Shanxi province(202203021212096),Shanxi Province Clinical Theranostics Technology Innova-tion Center for Immunologic and Rheumatic Diseases(CXZX-202302),and Research Project Plan of Shanxi Provincial Administration of Traditional Chinese Medicine(2023ZYYB2021).All authors are grateful for assistance from the following research platforms:Shanxi Province Clinical Research Center for Derma-tologic and Immunologic Diseases(Rheumatic dis-eases),Shanxi Province Clinical Theranostics Techno-logy Innovation Center for Immunologic and Rheum-atic Diseases. 山西白求恩医院人才引进科研启动基金(2022RC04),山西省基础研究计划项目(202203021212096),山西省免疫与风湿性疾病临床诊疗技术创新中心(CXZX-202302),山西省中医药管理局科研课题计划(2023ZYYB2021). （2022RC04）
