新医学2025，Vol.56Issue(1)：34-43,10.DOI:10.12464/j.issn.0253-9802.2024-0428
包头市变应性鼻炎吸入性变应原谱特征分析
Characteristics of inhalant allergen spectrum in patients with allergic rhinitis in Baotou City
摘要
Abstract
Objective To analyze the characteristics of inhalant allergen spectrum in patients with allergic rhinitis(AR)in Baotou,China.Methods The detection results of serum sIgE in 1 400 AR patients admitted to Department of Otorhinolaryngology,the First Affiliated Hospital of Baotou Medical College from January 2018 to December 2022 were retrospectively analyzed.The positive rates of 18 categories of allergens were compared in patients according to gender and age from 2018 to 2022.The distribution of single sensitization,multiple sensitization,and sensitization levels induced by 18 categories of allergens was also analyzed.Results The top 3 positive allergens were Artemisia 55.3%(774/1 400),cat epithelium 21.9%(307/1 400),and Chenopodium/Amaranthus retroflexus 18.0%(252/1 400).The positive rates of Dermatophagoides farinae,dog epithelium,Blattodea,and Humulus did not significantly change from 2018 to 2022(all P＞0.05),whereas those of the remaining 14 allergens changed significantly(all P＜0.05).Except for Humulus and Chenopodium/Amaranthus retroflexus,there were no significant differences in the positive rates of the remaining 16 categories of allergens between males and females(all P＞0.05).Except for Dermatophagoides pteronyssinus,Dermatophagoides farinae,Blomia tropicalis,dog epithelium,silk,Ambrosia,Humulus,Poa pratensis/Lolium/Phleum,there were significant differences in the positive rates of the remaining 10 categories of allergens among different age groups(all P＜0.05).In the middle-aged and elderly group,molds and Dermatophagoides were the main allergens secondary to Artemisia.The single sensitization rate of 18 categories of allergens was 32.8%and the multiple sensitization rate was 67.2%.The sIgE levels of Artemisia and cat epithelium at levels 5 and 6 were higher compared to those of other categories of allergens.Conclusions Artemisia is the main category of inhalant allergen in Baotou.The sIgE level is gradually increased over age,manifested with the pattern of multi-pollen sensitization.关键词
变应性鼻炎/变应原/特异性IgE/花粉Key words
Allergic rhinitis/Allergen/sIgE/Pollen引用本文复制引用
冯雅莉,王笑玥,苏日古格,郑奕,靳秀逸,陈博,王洪田,郭亚青..包头市变应性鼻炎吸入性变应原谱特征分析[J].新医学,2025,56(1):34-43,10.基金项目
首都卫生发展科研专项重点攻关项目(首发2024-1G-2082) （首发2024-1G-2082）
宁夏回族自治区重点研发计划(2024BEG02013) （2024BEG02013）
2024年包头医学院科研创新项目(BYKYCX202407) （BYKYCX202407）
