新医学2025，Vol.56Issue(1)：75-82,8.DOI:10.12464/j.issn.0253-9802.2024-0030
卵巢附件报告和数据系统结合超声造影的诊断效能:对123例附件肿块的分析
Diagnostic efficacy of Ovarian-Adnexal Reporting and Data System combined with contrast-enhanced ultrasound:analysis of 123 adnexal masses
摘要
Abstract
Objective To assess the diagnostic performance and inter-observer agreement of the Ovarian-Adnexal Reporting and Data System ultrasound(O-RADS)combined with contrast-enhanced ultrasound(CEUS).Methods Clinicopathological data of 123 adnexal lesions from 123 patients admitted to the University of Hong Kong-Shenzhen Hospital and the Seventh Affiliated Hospital of Sun Yat-sen University from July 2021 to December 2023 were collected.Each lesion was subject to CEUS before surgery.Each lesion was assigned to an O-RADS US category with histopathological results as the gold standard.The CEUS features of each lesion were recorded and used to calculate the total CEUS scores.Lesions were then re-rated according to O-RADS plus CEUS scores.Kappa(κ)statistics were applied to assess inter-observer agreement between a less experienced and an expert radiologist.Results Of the 123 adnexal lesions,94 were benign and 29 were malignant.The malignancy rates of O-RADS 5,O-RADS 4 and O-RADS 3 lesions were 81.25%,20.83%and 2.86%,respectively.The malignancy rates of O-RADS+CEUS 5,O-RADS+CEUS 4,O-RADS+CEUS 3 and O-RADS+CEUS 2 lesions were 75%,21.74%,0%and 0%,respectively.The area under the receiver operating characteristic(ROC)curve(AUC)of two observers were 0.791(95%CI 0.891-0.976)and 0.934(95%CI 0.697-0.886),respectively.The diagnostic performance of O-RADS plus CEUS was higher than that of O-RADS alone(P=0.0004).Taking≥O-RADS 4 as the cut-off value for malignant lesions,the sensitivity and specificity of O-RADS and O-RADS+CEUS were 0.966(95%CI,0.822-0.999)and 0.362(95%CI 0.265-0.467),1.000(95%CI 0.881-1.000)and 0.723(95%CI 0.622-0.811),respectively.The inter-observer agreement between a less experienced and an expert radiologist of O-RADS and CEUS features were good or very good(κ 0.668-0.840).Conclusions Compared with O-RADS,O-RADS plus CEUS shows better diagnostic specificity for malignant adnexal lesions.The inter-observer agreement between a less experienced and an expert radiologist of O-RADS and CEUS features is good.关键词
卵巢附件报告和数据系统/超声造影/卵巢附件肿块Key words
Ovarian-Adnexal Reporting and Data System/Contrast-enhanced ultrasound/Adnexal mass引用本文复制引用
华蓉,胡海云,朱云晓,李清莹,袁鲲..卵巢附件报告和数据系统结合超声造影的诊断效能:对123例附件肿块的分析[J].新医学,2025,56(1):75-82,8.基金项目
中山大学附属第七医院本科教学质量工程及教改项目(教务[2021]93号) （教务[2021]93号）
