神经药理学报2024，Vol.14Issue(5)：57-64,8.DOI:10.3969/j.issn.2095-1396.2024.05.008
右美托咪定在老年患者术后谵妄中的研究进展
Research Progress of Dexmedetomidine in Postoperative Delirium in Elderly Patients
摘要
Abstract
Postoperative delirium(POD)is a common complication after surgical anesthesia in elderly patients,especially after major surgery or emergency surgery,which interferes with the recovery process of patients and the prognosis of the primary disease,and may cause new complications to prolong the hospitalization cycle,increase the fatality rate and increase the medical cost of patients.Because the mechanism of POD is not clear,there is a lack of effective prevention measures.Recent studies have shown that Dexmedetomidine(DEX),as a highly selective α2 adrenergic receptor agonist,has shown certain advantages in POD prevention and treatment.In this paper,the related mechanisms and risk factors of POD,the clinical studies of dexmedetomidine in the prevention and treatment of POD in elderly patients and its potential mechanisms were reviewed,aiming to provide theoretical basis for clinical application.关键词
术后谵妄/右美托咪定/老年人/危险因素Key words
postoperative delirium/dexmedetomidine/aged/risk factor分类
医药卫生引用本文复制引用
张宇锡,姚杰..右美托咪定在老年患者术后谵妄中的研究进展[J].神经药理学报,2024,14(5):57-64,8.基金项目
河北省卫健委医学科研项目(No.20220607) （No.20220607）
河北省中医药类科学研究课题计划项目(No.2023332) （No.2023332）
