神经药理学报2024，Vol.14Issue(6)：50-57,8.DOI:10.3969/j.issn.2095-1396.2024.06.008
GABAA受体与中枢神经系统疾病研究进展
Research Progress of GABAA Receptor and Central Nervous System Diseases
摘要
Abstract
GABAA receptors are pentamers composed of multiple subunits,which not only determine the cellular location of GABAA receptors but also affect their biological functions.When the subunit is mutated,the receptor cannot effectively respond to GABA released by presynaptic neurons and glia,resulting in central nervous system diseases.This article will review the relationship between GABAA receptor and common diseases of central nervous system,and strive to provide theoretical basis for the treatment of these diseases.关键词
GABAA受体/中枢神经系统疾病/研究进展Key words
GABAA receptor/central nervous system diseases/research progress分类
医药卫生引用本文复制引用
张冉冉,张春月,吴志刚..GABAA受体与中枢神经系统疾病研究进展[J].神经药理学报,2024,14(6):50-57,8.基金项目
河北省研究生创新资助项目(No.CXZZSS2024129) （No.CXZZSS2024129）
河北北方学院校级科研项目(No.XJ2023034) （No.XJ2023034）
