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针刺干预脑梗死铁死亡机制研究探析

李泓涛 杜红根 李晶 杜元灏

针灸临床杂志2025,Vol.41Issue(1):7-12,6.
针灸临床杂志2025,Vol.41Issue(1):7-12,6.DOI:10.19917/j.cnki.1005-0779.025002

针刺干预脑梗死铁死亡机制研究探析

Exploring Mechanism Progress of Acupuncture in Intervening Ferroptosis in Cerebral Infarction

李泓涛 1杜红根 2李晶 3杜元灏3

作者信息

  • 1. 天津中医药大学第一附属医院,天津 300381||国家中医针灸临床医学研究中心,天津 300381||天津中医药大学,天津 301617||浙江省中医院,浙江 杭州 310003
  • 2. 浙江省中医院,浙江 杭州 310003
  • 3. 天津中医药大学第一附属医院,天津 300381||国家中医针灸临床医学研究中心,天津 300381
  • 折叠

摘要

Abstract

The domestic and international databases were searched to understand the progress of research on the mechanism of ferroptosis,also known as iron death,intervened by acupuncture in the last five years.Ferroptosis is a special cell-regulated mode of death that occurs widely throughout the body,and is different from the traditional cell death mode in that its pathology is characterized by iron overload,lipid peroxidation,and other oxidative damage.The mechanism of ferroptosis in cerebral infarction by acupuncture intervention has been verified in multiple disease models and signaling pathways.The pathogenesis of cerebral infarction is not completely clear at present,but it is closely related to ferroptosis.As a distinctive and effective intervention in Chinese medicine,acupuncture has certain advantages in regulating ferroptosis.However,some issues currently remain.It is anticipated that resolving these issues will provide new therapeutic insights for acupuncture intervention in the clinical treatment of cerebral infarction.

关键词

脑梗死/针刺/铁死亡/机制研究

Key words

Cerebral infarction/Acupuncture/Ferroptosis/Mechanism research

分类

医药卫生

引用本文复制引用

李泓涛,杜红根,李晶,杜元灏..针刺干预脑梗死铁死亡机制研究探析[J].针灸临床杂志,2025,41(1):7-12,6.

基金项目

国家自然科学基金,编号:82074543. ()

针灸临床杂志

1005-0779

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