中国现代医生2025，Vol.63Issue(2)：9-11,23,4.DOI:10.3969/j.issn.1673-9701.2025.02.003
瘢痕疙瘩术后放疗的疗效及影响因素分析
Analysis of the efficacy and influencing factors of radiotherapy after keloid surgery
摘要
Abstract
Objective To explore the efficacy of hypofractionated radiotherapy at different time intervals after surgery for keloid,and to analyze the factors affecting the efficacy.Methods A total of 76 patients who underwent 20 Gy/5 postoperative radiotherapy regimen in the Fifth Affiliated Hospital of Zhengzhou University from January 2021 to June 2023 were selected as study subjects,and a total of 100 keloids were divided into effective group(n=79)and recurrence group(n=21).Regular follow-up and record of the patients after radiotherapy treatment effect and adverse effects,and multivariate Logistic was used to analyze factors of recurrence in keloid patients.Results Multivariate Logistic regression analysis found that postoperative radiotherapy time and scar incision length were related to recurrence after treatment,radiotherapy within 7h of surgery was an independent risk factor for recurrence after treatment(OR＞1,P=0.022),and scar incision≤5cm was an independent protective factor for recurrence after treatment(OR＜1,P=0.028).Conclusion Surgical excision combined with hypofractionated radiotherapy is one of the effective measures to prevent and treat keloid recurrence,though keloids on the trunk may need more effective treatment options.The recurrence rate of radiotherapy initiated 7-48h after surgery is relatively the lowest,and it is worthy of clinical promotion and application.关键词
瘢痕疙瘩/放射治疗/复发/疗效Key words
Keloid/Radiotherapy/Recurrence/Efficacy分类
医药卫生引用本文复制引用
周笑笑,吴冬梅,田玉龙,段清源,李敏杰..瘢痕疙瘩术后放疗的疗效及影响因素分析[J].中国现代医生,2025,63(2):9-11,23,4.基金项目
河南省医学科技攻关计划项目(LHGJ20220568) （LHGJ20220568）
