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天山雪莲化学成分、药理活性研究进展及Q-marker预测

刘佩姿 张贤睿 陈可怡 张岩岩 苗莉娟 王新宇 蔡伟

中国现代中药2025,Vol.27Issue(2):228-241,14.
中国现代中药2025,Vol.27Issue(2):228-241,14.DOI:10.13313/j.issn.1673-4890.20240829005

天山雪莲化学成分、药理活性研究进展及Q-marker预测

Research Progress on Chemical Constituents and Pharmacological Activity of Saussurea involucrata and Q-marker Prediction

刘佩姿 1张贤睿 2陈可怡 1张岩岩 3苗莉娟 4王新宇 4蔡伟1

作者信息

  • 1. 湖南医药学院 药学院,湖南 怀化 418000
  • 2. 中国药科大学,江苏 南京 210009
  • 3. 新疆农业大学 食品科学与药学学院,新疆 乌鲁木齐 830000
  • 4. 新疆天山雪莲制药有限公司,新疆 阜康 831500
  • 折叠

摘要

Abstract

Saussurea involucrata is one of the traditional Chinese medicines,mainly distributed in the western highland areas of China,and it is widely used in the ethnic minority areas of China.Through methods such as high-performance liquid chromatography,anion exchange,and gel permeation chromatography,various compounds have been isolated from S.involucrata,including flavonoids,sesquiterpenoid lactones and their glycosides,phenylpropanoids,polysaccharides,and lignans.S.involucrata has pharmacological effects such as anti-inflammation and analgesia,protection of nerves,anti-tumor,anti-radiation,anti-obesity,and immune regulation.The research progress of S.involucrata in recent years was reviewed,and its quality markers(Q-makers)were predicted to provide a reference for its further study and application.

关键词

天山雪莲/化学成分/药理活性/质量标志物

Key words

Saussurea involucrata(Kar.et Kir.)Sch.-Bip./chemical constituent/pharmacological activity/quality marker

分类

医药卫生

引用本文复制引用

刘佩姿,张贤睿,陈可怡,张岩岩,苗莉娟,王新宇,蔡伟..天山雪莲化学成分、药理活性研究进展及Q-marker预测[J].中国现代中药,2025,27(2):228-241,14.

基金项目

新疆维吾尔自治区"十四五"重大科技专项(2022A03003) (2022A03003)

中国现代中药

1673-4890

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